Prognosis and immunotherapy efficacy in dMMR&MSS colorectal cancer patients and an MSI status predicting model.

The inconsistency between mismatch repair (MMR) protein immunohistochemistry (IHC) and microsatellite instability PCR (MSI-PCR) methods has been widely reported. We aim to investigate the prognosis and the effect of immunotherapy in dMMR by IHC but MSS by MSI-PCR (dMMR&MSS) colorectal cancer (CRC) patients. A microsatellite instability (MSI) predicting model was established to help find dMMR&MSS patients.

Testing region selection and prognostic analysis of promoter methylation in colorectal cancer in China.

Background: promoter methylation analysis is recommended in screening for Lynch syndrome (LS) in patients with MLH1-deficient colorectal cancer (CRC). The study aims to identify specific methylation regions in the promoter and to evaluate the clinicopathologic characteristics of and prognosis for patients with methylation.

Methods: A total of 580 CRC cases were included.

The Spectrum, Tendency and Predictive Value of Mutation in Chinese Colorectal Cancer Patients.

Background: is a high-frequency mutation gene in colorectal cancer, while its prognostic value remains unclear. This study evaluated the mutation tendency, spectrum, prognosis power and predictive power in cetuximab treatment of in Chinese CRC cohort.

Methods: The exon 9 and 20 status of 5763 CRC patients was detected with Sanger sequencing and a high-resolution melting test.

Complete chloroplast genome sequence of (Malvaceae): an endangered plant species.

(Malvaceae) is an evergreen tree distributed in the Chinese provinces of Hainan and Yunnan and in Cambodia. In China, it is listed as 'Endangered' (EN) , although it is not protected by law. The complete chloroplast (cp) genome sequence of this threatened species is reported in this study, based on high-throughput sequencing (Illumina).

Complete plastome sequence of (Erythropalaceae), an edible and medicinally important liana in China.

(Erythropalaceae, Santalales) is a large liana distributed in alluvial and riparian forests of Southeast Asia. Here we report and characterize the complete plastid genome sequence of in an effort to provide genomic resources useful for developing its medicinal and edible value. The complete plastome is 156,154 bp in length and contains the typical structure and gene content of angiosperm plastomes, including two Inverted Repeat (IR) regions of 26,394 bp, a large single-copy (LSC) region of 84,799 bp and a small single-copy (SSC) region of 18,567 bp.

The complete chloroplast genome sequence of (Melastomataceae), a shrub endemic to southern China.

The plant genus is monotypic, comprising of only a single species (), and is endemic to southern China. In this study, we report the complete chloroplast genome of , assembled from whole-genome high-throughput sequencing data, as a resource for future studies on the taxonomy and evolution of . The chloroplast genome was 155,951 bp in length, with a large single-copy (LSC) region of 85,882 bp, a small single-copy (SSC) region of 16,445 bp, separated by two inverted repeat (IR) regions of 26,812 bp each.

The complete chloroplast genome sequence of (Melastomataceae).

The plant genus is comprised of members estimated to have formed through recent species radiation. Natural hybridization among member species further complicates taxonomy within the genus. Herein, we report the complete chloroplast genome of , assembled from partial data obtained from a parallel whole-genome Illumina paired-end sequencing effort on the species.