Effect of interpregnancy interval on outcomes of pregnancy after recurrent pregnancy loss.

Objective: To examine the effect of interpregnancy interval (IPI) on outcomes of pregnancy after recurrent pregnancy loss (RPL).

Methods: A retrospective cohort study including 325 patients treated at a RPL clinic, with two or more consecutive pregnancy losses followed by a subsequent (index) pregnancy, of whom 163 had IPI ≤ 6 months, and 212 had IPI > 6 months.

Results: Pregnancy loss rate in the index pregnancy was positively associated with increased IPI (18.