Publications by authors named "YaYa Wang"

Thermally processed lipid- and protein-rich foods have sparked widespread concern since they may degrade food nutrition and even risk food safety. This study investigated soy protein isolate (SPI) alterations of digestibility and structure, as well as the formation of potentially hazardous chemicals, i.e.

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The microphysical changes in cloud formation and development are closely related to the vertical air motions. It is difficult to simultaneously detect microphysical parameters of drizzle and vertical air motions. This study proposes a method for the drizzle microphysical property and vertical air motions retrieval using Doppler lidar and radar measurements.

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Constructing donor-acceptor structures in polymeric carbon nitride (CN) provides an attractive pathway for facilitating charge carrier separation in photocatalytic reactions. However, achieving the implantation of donor or acceptor moieties at molecule level precision remains challenging. Here we develop a three-dimensional (3D) porous thiophene implanted carbon nitride (TCN) with donor-acceptor structure via a supramolecular assembly strategy.

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Article Synopsis
  • Diffuse large B-cell lymphoma (DLBCL) is a fast-growing type of cancer that makes up a significant portion of non-Hodgkin lymphoma cases, and it faces challenges like chemoresistance and immune evasion.
  • Research indicates that Sphingosine kinase 1 (SphK1) is highly expressed in DLBCL and its knockdown can enhance the effectiveness of chemotherapy (specifically doxorubicin) while improving immune response against the cancer cells.
  • Targeting SphK1 shows potential as a new therapeutic approach by inhibiting the PI3K/AKT/PD-L1 pathway, which plays a crucial role in helping DLBCL evade the immune system and resist treatment.
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Unlabelled: Accumulation of coal gangue (CG) poses significant risks to both human health and ecological systems, underscoring the urgent need for sustainable methods to utilize this abundant waste material effectively. In this study, we successfully screened and isolated the bacterial strain to enhance the solubilization of potassium (K) and phosphorus (P) nutrients from CG. The study employed XRD, FTIR, SEM, and HPLC techniques to investigate the underlying mechanisms of CG solubilization.

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Dipeptidyl peptidase 4 (DPP-4) inhibitors are new antidiabetic drugs. Their effects on the respiratory system remain unclear. This study aimed to determine the association between DDP-4 inhibitors and acute respiratory failure (ARF) among patients with type 2 diabetes mellitus (T2DM).

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Article Synopsis
  • * Researchers found that consuming ALEs led to harmful changes in gut bacteria and increased levels of neurotoxic Aβ peptides, which are associated with cognitive decline.
  • * The findings emphasize the connection between diet, gut health, and cognitive functioning, suggesting the need for dietary recommendations to limit ALE intake to lower the risk of neurodegenerative diseases.
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To develop an environmentally sustainable and efficient extraction method for flavonoids from Moringa oleifera Lam. (M. oleifera) leaves, natural deep eutectic solvents (NADES) with ultrasound-assisted extraction was utilized in this study.

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Developing an effective and convenient nitrite detection method is indispensable in food safety, environmental monitoring, clinical diagnosis of diseases, and many other areas. Herein, a dicyanoisophorone derivative, TMN-NH2 with large Stokes shift and near-infrared (NIR) emission, was proposed as a ratiometric fluorescence and colorimetric dual-mode probe for the rapid determination of NO in acidic media, showing excellent selectivity and high sensitivity. The sensing mechanism is based on the diazotization of TMN-NH2 with NO and subsequent diazonium salt hydrolysis to form a hydroxyl-substituted product (TMN-OH).

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Background: Pediatric cerebral palsy (CP) is a non-progressive brain injury syndrome characterized by central motor dysfunction and insufficient brain coordination ability. The etiology of CP is complex and often accompanied by diverse complications such as intellectual disability and language disorders, making clinical treatment difficult. Despite the availability of pharmacological interventions, rehabilitation programs, and spasticity relief surgery as treatment options for CP, their effectiveness is still constrained.

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Electrocatalytic nitrogen reduction reaction (NRR) is a green and highly efficient way to replace the industrial Haber-Bosch process. Herein, clusters consisting of three transition metal atoms loaded on CN as NRR electrocatalysts are investigated using density functional theory (DFT). Meanwhile, Ca was introduced as a promoter and the role of Ca in NRR was investigated.

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In recent years, with the continuous progress of DNA extraction and detection technology, cell-free DNA(cfDNA)has been widely used in the life science field, and its potential application value in forensic identification is becoming more and more obvious. This paper reviews the concept, formation mechanism, and classification of cfDNA, etc., and describes the latest research progress of cfDNA in personal identification of crime scene touch DNA samples and non-invasive prenatal paternity testing (NIPPT).

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Identification and the time since deposition (TsD) estimation of body fluid stains from a crime scene could provide valuable information for solving the cases and are always difficult for forensics. Microbial characteristics were considered as a promising biomarker to address the issues. However, changes in the microbiota may damage the specific characteristics of body fluids.

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Background: Both venetoclax plus a hypomethylating agent (VEN/HMA) and cytarabine, aclarubicin, and granulocyte colony-stimulating factor (CAG) are low-intensity regimens for older patients with acute myeloid leukemia (AML) that show good efficacy and safety. It is unknown how VEN/HMA compares with the CAG regimen for the treatment of newly diagnosed AML.

Methods: The outcomes of patients with newly diagnosed AML treated with VEN/HMA were compared with those of patients treated with a CAG-based regimen.

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Construction of a built-in electric field has been identified as an attractive improvement strategy for photoelectrochemical (PEC) water splitting by facilitating the carrier extraction from the inside to the surface. However, the promotion effect of the electric field is still restrained by the confined built-in area. Herein, we construct a microscale built-in electric field gradient oxygen doping.

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Aim: This study aims to investigate the clinical value of the Duke Anesthesia Resistance Scale (DARS) in predicting postoperative delirium (POD) after hip fracture surgery.

Methods: A retrospective study was conducted. Clinical data were collected from the patients who had hip fracture and underwent elective total hip arthroplasty in Shaanxi Provincial People's Hospital, Third Affiliated Hospital of Xi'an Jiaotong University between January 2022 and June 2023.

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Sleep problems in middle-aged and older people can threaten their physical and mental health. Family support is regarded as a key factor that affects sleep quality, but the influence mechanism remains underexplored. This study analyzes the mediating effects of fear of crime (FOC) and loneliness in the relationship between family support and sleep quality, and explores whether gender plays a moderating role between family support and FOC.

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In order to calibrate the contact parameters, particle models for mixtures of each period were established by simulation of repose angle using combined models in EDEM software, and then the flow properties of mixtures in different aerobic composting periods were clarified. Results showed that compared with the six-sphere model, the use of the double-sphere model to represent the compost mixtures of each period was not only closer to the ellipsoid of the actual particles but also simplified the calculation process. The contact parameters that mostly affected the repose angle were Poisson's ratio and shear modulus of mixture in the mesophilic period and JKR surface energy in thermophilic and cooling periods.

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Background: Postoperative complications are important factors affecting the survival time and quality of life of patients undergoing radical gastrectomy.

Aim: To investigate and compare the anesthetic effects of intravenous general anesthesia combined with epidural anesthesia or ultrasound-guided bilateral transversus abdominal plane block (TAPB) in gastric cancer patients undergoing laparoscopic radical gastrectomy.

Methods: The clinical data of 85 patients who underwent laparoscopic radical gastrectomy in our hospital from December 2020 to January 2023 were retrospectively collected and divided into a TAPB group ( = 45) and epidural anesthesia group ( = 40) according to the different anesthesia and analgesia programs used.

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Ethnopharmacological Relevance: Zhi-Zi-Hou-Po decoction (ZZHP), a traditional Chinese medicine (TCM) classic recipe, has been extensively applied for the remedy of depression. However, the underlying mechanism of ZZHP hasn't been fully elucidated and it needs to be further clarified.

Aim Of Study: The aim of the study is to uncover the mechanisms of ZZHP's effect on depression.

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Advanced lipoxidation end products (ALEs) are formed by modifying proteins with lipid oxidation products. The health effects of ALEs formed have been extensively studied. However, the digestibility, safety, and health risk of ALEs in heat-processed foods remain unclear.

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The problems of inaccurate detection values of thermal-processed β-lactoglobulin (β-LG) content seriously affect the screening of allergens. A monoclonal antibody (mAb) against β-LG was successfully prepared and a highly sensitive sandwich ELISA (sELISA) was constructed with specific nanobody (Nb) as the capture antibody with detection limit of 0.24 ng/mL.

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With the development of aquaculture, wastewater treatment and diseases have been paid more and more attention. The question of how to improve the immunity of aquatic species, as well as treat aquaculture wastewater, has become an urgent problem. In this study, duckweed with a high protein content (37.

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The microbial communities on shoe soles and shoeprints could carry microbial information about where someone walked. This is possible evidence to link a suspect in a crime case to a geographic location. A previous study had shown that the microbiota found on shoe soles depend on the microbiota of the soil on which people walk.

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