One-step gas-phase syntheses of few-layered single-phase TiNCl and TiCCl MXenes with high stabilities.

With the iteration of etching techniques, MXenes have exhibited astounding accomplishments. Nevertheless, intricate procedures, expensive precursors, and degradation present obstacles for practical application. Although chemical vapor deposition has been developed as a solution, direct syntheses of few-layered single-phase MXenes remain an open challenge, especially for TiNCl.

Numerical Simulation of Electromagnetic Nondestructive Testing Technology for Elasto-Plastic Deformation of Ferromagnetic Materials Based on Magneto-Mechanical Coupling Effect.

A numerical tool for simulating the detection signals of electromagnetic nondestructive testing technology (ENDT) is of great significance for studying detection mechanisms and improving detection efficiency. However, the quantitative analysis methods for ENDT have not yet been sufficiently studied due to the absence of an effective constitutive model. This paper proposed a new magneto-mechanical model that can reflect the dependence of relative permeability on elasto-plastic deformation and proposed a finite element-infinite element coupling method that can replace the traditional finite element truncation boundary.

Overcoming multiple barriers to deliver photo-gene system for glioma-targeted combined therapy.

Overcoming multiple barriers to deliver macromolecular drugs is an urgent challenge for glioma treatment. Herein, a strategy of protein corona-regulation synergizing with photoactivation based on T10 peptide-modified and indocyanine green (ICG)-loaded dendrigraft poly-L-lysines was proposed to augment prime editing therapy of glioma. First, the modified T10 peptide could escape the interference barrier of protein crown in blood via its specific binding with endogenous transferrin, thus crossing the blood-brain barrier (BBB) and achieving the targeting recognition of glioma cells.

Application of Multi-Rod Constructs for the Revision of Thoracolumbar Fractures.

Objective: The revision procedure for failure of internal fixation after thoracolumbar fracture is controversial. Combined anterior and posterior surgery is associated with higher risk more intraoperative bleeding and tissue damage. The success rate of simple anterior surgery needs further confirmation, and posterior surgery lacks stability of internal fixation.

Gas-phase synthesis of TiCCl enables an efficient catalyst for lithium-sulfur batteries.

MXenes have aroused intensive enthusiasm because of their exotic properties and promising applications. However, to date, they are usually synthesized by etching technologies. Developing synthetic technologies provides more opportunities for innovation and may extend unexplored applications.

High-throughput screening of ancient forest plant extracts shows cytotoxicity towards triple-negative breast cancer.

According to the World Health Organization, women's breast cancer is among the most common cancers with 7.8 million diagnosed cases during 2016-2020 and encompasses 15 % of all female cancer-related mortalities. These mortality events from triple-negative breast cancer are a significant health issue worldwide calling for a continuous search of bioactive compounds for better cancer treatments.

Ancient forest plants possess cytotoxic properties causing liver cancer HepG2 cell apoptosis.

Here, we collected 154 plant species in China ancient forests looking for novel efficient bioactive compounds for cancer treatments. We found 600 bioactive phyto-chemicals that induce apoptosis of liver cancer cell in vitro. First, we screen the plant extract's in vitro cytotoxicity inhibition of cancer cell growth using in vitro HepG2 cell lines and MTT cytotoxicity.

Phytosphere purification of urban domestic wastewater.

Industrialization and overpopulation have polluted aquatic environments with significant impacts on human health and wildlife. The main pollutants in urban sewage are nitrogen, phosphorus, heavy metals and organic pollutants, which need to be treated with sewage, and the use of aquatic plants to purify wastewater has high efficiency and low cost. However, the effectiveness and efficiency of phytoremediation are also affected by temperature, pH, microorganisms and other factors.

Enhanced Yield of Large-Sized TiCT MXene Polymers Nanosheets via Cyclic Ultrasonic-Centrifugal Separation.

Water pollution has spurred the development of membrane separation technology as a potential means of solving the issue. In contrast to the irregular and asymmetric holes that are easily made during the fabrication of organic polymer membranes, forming regular transport channels is essential. This necessitates the use of large-size, two-dimensional materials that can enhance membrane separation performance.

Highly Luminescent Nonclassical Binuclear Manganese(II) Complex Scintillators for Efficient X-ray Imaging.

Scintillators can be widely applied to the fields of radioactivity detection, space exploration, and medical diagnosis and have attracted great attention. Recently, manganese(II) complexes with high-efficiency phosphorescent emission are expected to be good candidates for new scintillator materials. Herein, we design and synthesize a series of novel nonclassical binuclear neutral manganese(II) complexes with unique coordination modes, in which the crystal structures of and contain both four-coordinated and six-coordinated manganese(II) centers and is formed as a binuclear five-coordinated dichloro-bridged dimer.

Biodegradable and Cytocompatible Hydrogel Coating with Antibacterial Activity for the Prevention of Implant-Associated Infection.

Implant-associated infection (IAI) caused by pathogens colonizing on the implant surface is a serious issue in the trauma-orthopedic surgery, which often leads to implant failure. The complications of IAI bring a big threat to the clinical practice of implants, accompanied by significant economic cost and long hospitalization time. In this study, we propose an antibiotics-free strategy to address IAI-related challenges by using a biodegradable and cytocompatible hydrogel coating.

Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression.

Osteosarcoma (OS) is the most common bone tumour with a high risk of metastatic progression and recurrence after treatment. Circular RNA hsa_circ_0000591 (circ_0000591) plays a compelling role in OS aggressiveness. However, the function and regulatory mechanism of circ_0000591 need to be further elucidated.

Phytoremediation of cadmium from soil, air and water.

Potentially toxic elements (PTEs) pose a great threat to ecosystems and long-term exposure causes adverse effects to wildlife and humans. Cadmium induces a variety of diseases including cancer, kidney dysfunction, bone lesions, anemia and hypertension. Here we review the ability of plants to accumulate cadmium from soil, air and water under different environmental conditions, focusing on absorption mechanisms and factors affecting these.

Nano Ag/CoO Catalyzed Rapid Decomposition of Bark for Production Biofuels and Biochemicals.

Biomass energy has attracted widespread attention due to its renewable, storage, huge production and clean and pollution-free advantages. Using bark (RPB) as raw material, biogas and bio-oil produced by pyrolysis of RPB were detected and analyzed by TG-DTG, TG-FTIR and PY-GC-MS under the action of nanocatalysis. TG results showed that CH and CO flammable gases were produced by pyrolysis.

A discussion of microplastics in soil and risks for ecosystems and food chains.

Microplastics are among the major contaminations in terrestrial and marine environments worldwide. These persistent organic contaminants composed of tiny particles are of concern due to their potential hazards to ecosystem and human health. Microplastics accumulates in the ocean and in terrestrial ecosystems, exerting effects on living organisms including microbiomes, fish and plants.

Multicomponent integrated care for patients with chronic heart failure: systematic review and meta-analysis.

To investigate the effectiveness of multicomponent integrated care on clinical outcomes among patients with chronic heart failure. We conducted a meta-analysis of randomized clinical trials, published in English language from inception to 20 April 2022, with at least 3-month implementation of multicomponent integrated care (defined as two or more quality improvement strategies from different domains, viz. the healthcare system, healthcare providers, and patients).

Incorporation of Nanocatalysts for the Production of Bio-Oil from Wood.

Biomass has been recognized as the most common source of renewable energy. In recent years, researchers have paved the way for a search for suitable biomass resources to replace traditional fossil fuel energy and provide high energy output. Although there are plenty of studies of biomass as good biomaterials, there is little detailed information about wood () as a potential bio-oil material.

Impact of multicomponent integrated care on mortality and hospitalization after acute coronary syndrome: a systematic review and meta-analysis.

Aims: Multicomponent integrated care is associated with sustained control of multiple cardiometabolic risk factors among patients with type 2 diabetes. There is a lack of data in patients with acute coronary syndrome (ACS). We aimed to examine its efficacy on mortality and hospitalization outcomes among patients with ACS in outpatient settings.

A Space-Time Conversion Vehicle for Programmed Multi-Drugs Delivery into Pancreatic Tumor to Overcome Matrix and Reflux Barriers.

The numerous biological barriers, which limit pharmacotherapy of pancreatic carcinoma, including inadequate drug accumulation in the tumor environment, a dense extracellular matrix (ECM) and efficient drug-efflux mechanisms, illustrate the requirement of multifunctional delivery systems to overcome the individual barriers at the right place at the right time. Herein, a space-time conversion vehicle based on covalent organic framework (COF)-coated mesoporous silica nanospheres (MSN) with a sandwiched polyethyleneimine (PEI) layer (MPCP), is designed. The space-specific drugs-loaded vehicle (M P C P) is obtained by separately incorporating a chemotherapeutic agent (gemcitabine, G) into the MSN core, a P glycoprotein inhibitor (LY 335979, P) into the PEI layer, and an extracellular matrix disruptor (losartan, L) into the COF shell.

Effects of purifiers on the airborne transmission of droplets inside a bus.

During an airborne infectious disease outbreak, bus passengers can be easily infected by the dispersion of exhaled droplets from an infected passenger. Therefore, measures to control the transport of droplets are necessary, such as a mask or purifier. The current research examined aerosol transport in a bus with air-conditioning.

[Acupoint thread-embedding as adjuvant therapy for bronchial asthma in children and its effect on pulmonary function, serum IgA and IgE levels].

Objective: To observe the efficacy of acupoint thread-embedding combined with fluticasone propionate aerosol for chronic persistent bronchial asthma of lung-spleen deficiency and spleen-kidney deficiency in children and its effect on pulmonary function and serum levels of IgA and IgE.

Methods: A total of 120 children with chronic persistent bronchial asthma were randomly divided into an observation group (60 cases, 9 cases dropped off) and a control group (60 cases, 7 cases dropped off). The control group was treated with fluticasone propionate aerosol (125 μg per inhalation), twice a day; based on the control group treatment, the observation group was treated with acupoint thread-embedding at Dingchuan (EX-B 1), Feishu (BL 13), Zusanli (ST 36) and Danzhong (CV 17), once half a month.