Publications by authors named "Ya-ya Zhang"
Article Synopsis
- Acute lung injury (ALI) is a serious inflammatory condition linked to high rates of illness and death, often driven by inflammatory cytokines released by macrophages.
- Tulipalin A, an active compound in anti-inflammatory sesquiterpene lactones, shows promise in reducing inflammation associated with ALI, though its full potential is still being explored.
- The study reveals that Tulipalin A works by targeting and disrupting the DNA binding of NF-κB p65, ultimately reducing macrophage activation and inflammatory responses, which may help treat conditions like ALI.
Background: Osteoporosis, a systemic metabolic bone disease, is often caused by the disruption of dynamic equilibrium between osteoclasts and osteoblasts. Overactive bone resorption, in which osteoclasts play a major role, is one of the most common and major causes of osteoporosis. Less costly and more effective drug treatments for this disease are needed.
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- Over the past 5 years, high levels of paralytic shellfish toxins (PSTs) have been found in mussels around Qinhuangdao due to toxic outbreaks from Alexandrium dinoflagellates.
- A study conducted from 2017 to 2020 used advanced techniques to confirm that Alexandrium catenella was the main producer of these toxins, notably gonyautoxins (GTX1/4 and GTX2/3).
- Environmental factors, such as increased water temperature and calm weather, contributed to the blooms, and monitoring dissolved toxins in seawater proved to be an effective method for early detection of potential poisoning risks.
Harmful red tides in China have caused paralytic shellfish toxins (PSTs) pollution and led to severe socioeconomic effects in shellfish aquaculture. Although shellfish can survive harmful algal blooms, the effects on their Condition Index (CI) have been underestimated. This study sought to evaluate the effects of the profiles and levels of paralytic shellfish toxins on variations in the CI in bivalves under natural blooming conditions.
View Article and Find Full Text PDFObjective: To investigate the correlation between common peaks of Angelica sinensis HPLC fingerprint and mineral elements in its growing soil.
Methods: The fingerprints of 120 batches of Angelica sinensis from 12 habitats were determined by HPLC. The contents of Pb, As, Cr, Sb, Hg, Cu, Cd, Ni, Zn, Mg, Mn, Ca, Fe, Na and K in corresponding soil were determined by ICP-MS and AAS.
Objective: To investigate the spectrum characteristics of near-intrared dittuse retlectance spectroscopy (NIR) fingerprint of different medicinal parts of Angelicae Sinensis Radix.
Methods: 96 batches of samples were collected from 14 counties of Gansu Province and Yunnan Province. The NIR fingerprints were collected by integrated sphere.
Objective: To investigate the distribution characteristics of mineral elements in the soil of Angelica sinensis producing regions and its relationship with altitude and soil types.
Methods: The contents of 15 mineral elements in 103 batches of soil from 13 counties were determined by ICP-MS or AAS. Pearson correlation analysis, partial correlation analysis and systematical cluster analysis were used to analyze the data.
Osteopontin (OPN) has been implicated in tumor development and progression over the last few years. However, the prognostic value of OPN overexpression in patients with breast cancer remains controversial. We performed a meta-analysis to investigate the association of OPN expression in the tumor with the clinicopathological characteristics and survival of breast cancer patients.
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