PRAME is a useful marker for the differential diagnosis of melanocytic tumours and histological mimics.

Aims: Although the morphological assessment of melanoma is generally straightforward, diagnosis can be especially difficult when the significant morphological and immunohistochemical results overlap with those of benign and malignant melanocytic tumours and histological mimics. This study assessed the potential diagnostic utility of measuring PReferentially expressed Antigen in MElanoma (PRAME) immunohistochemically in naevi, melanomas and clear cell sarcomas (CCSs) in Chinese patients.

Methods: We examined the immunohistochemical expression of PRAME in 317 melanocytic naevi, 178 primary melanomas, 72 metastatic melanomas and 19 CCSs and compared the sensitivity and specificity of PRAME immunohistochemistry (IHC) in the differential diagnosis of melanocytic tumours and histological mimics.

Changes of the condylar position after modified disk repositioning: A retrospective study based on magnetic resonance imaging.

Objective: This study aimed to explain the malocclusion resulting from the changes in condylar position after unilateral open disk repositioning surgery.

Study Design: Patients treated with unilaterally modified temporomandibular joint disk repositioning were reviewed. All patients underwent magnetic resonance imaging (MRI) before and immediately after surgery.

Can a Novel Surgical Approach to the Temporomandibular Joint Improve Access and Reduce Complications?

Purpose: This clinical study investigated whether the vascular-guided multilayer preauricular approach (VMPA) to the temporomandibular joint (TMJ) could improve access and decrease complications.

Patients And Methods: This retrospective evaluation consisted of a consecutive series of patients who underwent TMJ surgeries through the VMPA from January through December 2013. Patients with a history of TMJ surgery were excluded.

Primary intra- and juxta-articular vascular malformations of the temporomandibular joint: a clinical analysis of 8 consecutive patients.

Objective: To analyze primary intra- and juxta-articular vascular malformations of the temporomandibular joint.

Patients And Methods: This study retrospectively reviewed eight patients (seven venous malformations and one lymphatico-venous malformation) who were treated for intra- or juxta-articular vascular malformations of the temporomandibular joint from November 2005 to January 2011. All patients underwent magnetic resonance imaging (MRI) preoperatively.

Synovial chondromatosis of the tempromandibular joint: relationship between MRI information and potential aggressive behavior.

Purpose: To evaluate the types of synovial condromatosis (SC) of tempromandibular joint (TMJ) on MRI and their potential aggressive behavior.

Methods: 144 patients with pure SC of TMJ were included in. On MRI, 3 types of the lesion included loose body, homogeneous mass, and mixture of both loose body and homogeneous mass.

Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension.

Pigmented villonodular synovitis is an uncommon benign tumor-like proliferative lesion with an undetermined origin. Involvement of the temporomandibular joint is uncommon. Although pigmented villonodular synovitis is a benign lesion, it can grow with an aggressive pattern, and it extends extra-articularly in most of the reported cases, about one-third of them exhibiting intracranial involvement.

Post-infectious myositis ossificans in medial, lateral pterygoid muscles: A case report and review of the literature.

Myositis ossificans (MO) is a disease where heterotropic bone forms within a muscle or other type of soft tissue. MO is classified into two groups, MO progressiva and post-traumatic MO. It rarely occurs in the masticatory muscles and thus, only 20 cases involving the masticatory muscles have been reported since 2001.

Osteochondroma of the mandibular condyle: a classification system based on computed tomographic appearances.

Objective: The objectives of this study were to introduce the classification of osteochondroma of the mandibular condyle based on computed tomographic images and to present our treatment experiences.

Materials And Methods: From January 2002 and December 2012, a total of 61 patients with condylar osteochondroma were treated in our division. Both clinical and radiologic aspects were reviewed.

Synovial TGF-β1 and MMP-3 levels and their correlation with the progression of temporomandibular joint osteoarthritis combined with disc displacement: A preliminary study.

Osteoarthritis (OA) is a slow progressing degenerative disease that affects the joints, including the temporomandibular joint. In the present study, transforming growth factor-β1 (TGF-β1) and matrix metalloproteinase 3 (MMP-3) in synovial fluid (SF) were examined in detecting cartilage synthesis and degradation in progression of temporomandibular joint osteoarthritis (TMJ OA) combined with disc displacement (DD) diseases. SF was obtained from 16 patients with TMJ OA combined with DD and 10 normal volunteers.

Local resection of the mass to treat the osteochondroma of the mandibular condyle: indications and different methods with 38-case series.

Background: Local resection of the mass was reported to treat the condylar osteochodroma in some cases. The purpose of this study was to evaluate the feasibility and the indications of the local resection.

Methods: In all, 47 patients with osteochondroma of the mandibular condyle were treated from January 2002 to March 2012.

Metastatic spread to the mandibular condyle as initial clinical presentation: radiographic diagnosis and surgical experience.

Purpose: Metastatic spread to the mandibular condyle is uncommon. The authors retrospectively evaluated a series of consecutive cases of condylar metastases presenting as the initial clinical event to increase awareness and provide a better understanding of this occurrence.

Patients And Methods: This study consisted of 6 cases of metastatic tumor of the mandibular condyle presenting as the initial clinical event from July 2004 to May 2011.

[A primary application and evaluation of temporomandibular joint replacement with stock prosthesis].

Purpose: To evaluate the effect of total joint replacement in treatment of temporomandibular joint(TMJ) osteoarthropathy with stock prostheses.

Methods: Six female patients involving 10 joints (2 unilateral and 4 bilateral), with an average age of 59 years old, were involved in this study. Three patients (5 joints) were diagnosed as internal derangement in V stage depending on MRI, 3D-CT findings and clinical characteristics.

Malignant hemangiopericytoma of the condyle.

Hemangiopericytoma (HPC) is an uncommon vascular tumor arising from pericytic cells with variable malignant potential. Primary HPCs of the bone are extremely rare; however, involvement of the condylar process has not been reported. We presented a 21-year-old female patient with low-grade malignant HPC in the right mandibular condyle.

Preauricular transcondylar approach for basal cell adenoma of parotid coexist with ganglion cyst of the ipsilateral temporomandibular joint.

The concurrence of 2 independent neoplasias in the ipsilateral parotid and the temporomandibular joint (TMJ) region was infrequently reported. In this article, we present a unique case characterized by the coexistence of a rare salivary gland tumor, basal cell adenoma, of the parotid gland with a ganglion cyst in the ipsilateral TMJ region. A special surgical procedure was also presented here using a modified preauricular incision and transcondylar approach for extracapsular dissection of both lesions.

Synovial chondromatosis in the inferior compartment of the temporomandibular joint: different stages with different treatments.

Purpose: To discuss a new classification and the treatment principles of synovial chondromatosis (SC) in the inferior compartment of the temporomandibular joint (TMJ).

Patients And Methods: Five cases of SC in the inferior compartment were treated in an open manner between January 2008 and May 2011. Each case had different clinical and radiologic aspects and was treated with different surgical therapies.

Synovial chondromatosis originally arising in the lower compartment of temporomandibular joint: a case report and literature review.

Introduction: More than 200 cases of synovial chondromatosis (SC) in the TMJ were reported. Most of SC described exclusively involved the upper compartment of the joint. SC originally arising in the lower compartment is rarely found.

Endoscopically assisted reconstruction of the mandibular condyle with a costochondral graft through a modified preauricular approach.

We describe our experience with reconstruction of the mandibular condyle with a costrochondral graft (CCG). We retrospectively evaluated 122 patients with diagnoses including osteoarthrosis, ankylosis, tumours, idiopathic condylar resorption, comminuted condylar fracture, and chronic osteomyelitis of the temporomandibular joint (TMJ). We used a modified preauricular approach and an endoscopically assisted technique.

[The clinical application of arthroscope-assisted reconstruction of the mandibular condyle with costochondral graft].

Objective: This is a preliminary study of the endoscopic technique on open surgery. The purpose of this study is to introduce the use of endoscopic technique for the reconstruction of the condyle with costochondral graft through a preauricular incision.

Methods: 33 patients of temporomandibular joint diseases (n=49) underwent reconstruction of mandibular condyle with costochondral graft.