Ozonated oil increases the healing of chronic diabetic wounds, but the underlying mechanisms remain unclear. We investigated the effect of topical ozonated oil on wound healing in mice with diabetes with diet-induced obesity and further elucidated the role of EGFR and IGF1R signaling in diabetic wound healing. We found that topical ozonated oil accelerated wound healing; increased phosphorylation of IGF1R, EGFR, and VEGFR; and improved vascularization at the wound leading edge in mice with diabetes with diet-induced obesity.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
December 2007
Nan Fang Yi Ke Da Xue Xue Bao
June 2006
Objective: To survey mycoplasma infection in female urogenital tract and analyze the drug sensitivity of mycoplasma in Changsha.
Methods: Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) were detected in 6566 cases of female urogenital tract infection by means of mycoplasma culture and drug sensitivity reagent kit. Sensitivity tests for 10 antibiotics were also performed.
Zhongguo Zhong Xi Yi Jie He Za Zhi
August 2003
Objective: To observe the therapeutic effect of Xiaobai Mixture (XBM) in treating vitiligo.
Methods: Seventy-four patients with vitiligo were randomly divided into the XBM group treated with XBM and the control group treated with 8-MOP. The therapeutic effect, nail-fold microcirculation, plasma endothelin-1, serum immunoglobulin were observed and compared.