The value of machine learning based on CT radiomics in the preoperative identification of peripheral nerve invasion in colorectal cancer: a two-center study.

Background: We aimed to explore the application value of various machine learning (ML) algorithms based on multicenter CT radiomics in identifying peripheral nerve invasion (PNI) of colorectal cancer (CRC).

Methods: A total of 268 patients with colorectal cancer who underwent CT examination in two hospitals from January 2016 to December 2022 were considered. Imaging and clinicopathological data were collected through the Picture Archiving and Communication System (PACS).

Individualized driver amplitude in liver MR elastography: a linear regression study.

Background: Current liver magnetic resonance elastography (MRE) scans often require adjustments to driver amplitude to produce acceptable images. This could lead to time wastage and the potential loss of an opportunity to capture a high-quality image.

Purpose: To construct a linear regression model of individualized driver amplitude to improve liver MRE image quality.

The physicochemical characteristics and antidepressant-like effects of a polysaccharide-rich fraction from Schisandra chinensis (Turcz.) Baill in behavioral despair mice and olfactory bulbectomy-induced depression-like mice.

Ethnopharmacological Relevance: The dried fruit of Schisandra chinensis (Turcz.) Baill (S. chinensis) is widely used in treating central nervous system disorders.

Covalent Organic Framework-Based Nanomotor for Multimodal Cancer Photo-Theranostics.

Developing efficient integrated diagnosis and treatment agents based on fuel-free self-movement nanomotors remains challenging in antitumor therapy. In this study, a covalent organic framework (COF)-based biomimetic nanomotor composed of polypyrrole (PPy) core, porphyrin-COF shell, and HCT116 cancer cell membrane coating is reported. Under near-infrared (NIR) light irradiation, the obtained mPPy@COF-Por can overcome Brownian motion and achieves directional motion through self-thermophoretic force generated from the PPy core.

A simpler noninvasive method of predicting markedly elevated pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension.

Several echocardiographic methods to estimate pulmonary vascular resistance (PVR) have been proposed. So far, most studies have focused on relatively low PVR in patients with a nonspecific type of pulmonary hypertension. We aimed to clarify the clinical usefulness of a new echocardiographic index for evaluating markedly elevated PVR in chronic thromboembolic pulmonary hypertension (CTEPH).

The accuracy and influencing factors of Doppler echocardiography in estimating pulmonary artery systolic pressure: comparison with right heart catheterization: a retrospective cross-sectional study.

Background: Noninvasive assessment of pulmonary artery systolic pressure by Doppler echocardiography (sPAP) has been widely adopted to screen for pulmonary hypertension (PH), but there is still a high proportion of overestimation or underestimation of sPAP. We therefore aimed to explore the accuracy and influencing factors of sPAP with right heart catheterization (RHC) as a reference.

Methods: A total of 218 highly suspected PH patients who underwent RHC and echocardiography within 7 days were included.

Diagnostic role of 18F-FDG PET/MRI in the TNM staging of breast cancer: a systematic review and meta-analysis.

Background: To investigate the value of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) in diagnosing local tumor invasion (T stage), evaluating regional lymph node involvement (N stage), and detecting distant metastasis (M stage) in breast cancer patients.

Methods: A comprehensive computer search and manual search were performed to select any potentially eligible studies that evaluated the diagnostic efficacy of 18F-FDG PET/MRI in the tumor-node-metastasis (TNM) staging of breast cancer. Data from the included studies were extracted to calculate the pooled sensitivity, specificity, and area under the curve (AUC) to evaluate the value of 18F-FDG PET/MRI in TNM staging.

Regional right ventricular longitudinal systolic strain for detection of severely impaired right ventricular performance in pulmonary hypertension.

Objectives: Right ventricular (RV) function is identified as a key determinant of the outcome in patients with pulmonary hypertension (PH). Several studies have assessed the role of peak global longitudinal RV strain in PH patients; however, less emphasis was given to the RV regional longitudinal strain. The aim of this study was to evaluate the regional RV systolic strain in PH patients and investigate the relationship of these parameters with the severity of PH.

Whole-Liver Apparent Diffusion Coefficient Histogram Analysis for the Diagnosis and Staging of Liver Fibrosis.

Background: Conventional diffusion-weighted imaging is limited in the quantitative evaluation of liver fibrosis, and whole-liver apparent diffusion coefficient (ADC) histogram analysis might contribute to the diagnosis and staging of liver fibrosis.

Purpose: To explore the value of whole-liver ADC histogram parameters in the diagnosis and staging of liver fibrosis.

Study Type: Retrospective.

Cyanogel auto-reduction induced synthesis of PdCo nanocubes on carbon nanobowls: a highly active electrocatalyst for ethanol electrooxidation.

Direct ethanol fuel cells (DEFCs) with a high conversion efficiency are quite promising candidates for energy conversion devices. Herein, we have successfully synthesized PdCo alloy nanocubes supported on carbon nanobowl (denoted as PdCo/CNB) nanohybrids by using the cyanogel auto-reduction method at high temperature. The morphology, composition and structure of PdCo/CNB nanohybrids are characterized in detail, revealing that PdCo nanocubes have a high alloying degree and special {110} facets.

The value of speckle-tracking echocardiography in identifying right heart dysfunction in patients with chronic thromboembolic pulmonary hypertension.

Right ventricular (RV) function is a significantly important factor in the determination of the prognosis of chronic thromboembolic pulmonary hypertension (CTEPH) patients. Speckle-tracking echocardiography (STE) is an angle-independent new technique for quantifying myocardial deformation that is capable of providing data on multiple parameters including longitudinal and transverse information of the myocardium. In the present study, we aimed to study the advantages of STE-derived parameters in identifying RV dysfunction in CTEPH patients.

Atoms diffusion-induced phase engineering of platinum-gold alloy nanocrystals with high electrocatalytic performance for the formic acid oxidation reaction.

Bimetallic noble metal nanocrystals have been widely applied in many fields, which generally are synthesized by the wet-chemistry reduction method. This work presents a purposely designed atoms diffusion induced phase engineering of PtAu alloy nanocrystals on platy Au substrate (PtAu-on-Au nanostructures) through simple hydrothermal treatment. Benefitting from the synergistic effects of component and structure, PtAu-on-Au nanostructures remarkably enhance the dehydrogenation pathway of the formic acid oxidation reaction (FAOR), and thus exhibit much higher FAOR activity and durability compared with Pt nanocrystals on platy Au substrate (Pt-on-Au nanostructures) and commercial Pd black due to an excellent stability of platy Au substrate and a high oxidation resistance of PtAu alloy nanocrystals.

Characterization of a cluster of CTCF-binding sites in a protocadherin regulatory region.

The mammalian clustered protocadherin (Pcdh) locus contains more than 50 highly-similar genes arrayed in tandem. These Pcdh genes are organized into three closely-linked clusters (Pcdhα, Pcdhβ, and Pcdhγ). The encoded PCDH proteins play critical roles in neuronal diversity, single cell identity, and synaptic connectivity.

Incidences of aortic and mitral valve strands in patients with migraine with aura.

Objective: To analyze the potential association between valvular strands and migraine with aura.

Methods: During a 1-year period,transesophageal echocardiography was performed in 51 consecutive patients with migraine with aura and 75 control subjects who underwent transesophageal echocardiography for other purposes and had no history of migraine. The presence of aortic and mitral valve strands was evaluated.

Which technique is better for detection of right-to-left shunt in patients with patent foramen ovale: comparing contrast transthoracic echocardiography with contrast transesophageal echocardiography.

Background: At present there is no consensus on which technique is more suitable for the detection of right-to-left shunt (RLS) in patients with patent foramen ovale (PFO). The aim of study was to compare the efficacy of contrast transthoracic echocardiography (cTTE) and contrast transesophageal echocardiography (cTEE) in the detection of RLS.

Methods: A prospective study was undertaken in 29 patients with PFO.

[Effect of propranolol gel on infantile hemangiomas].

Objective: To evaluate the efficacy and security of propranolol gel in treatment of Infantile hemangiomas.

Methods: 51 consecutive infants with hemangiomas from October 2010 to September 2011 in Department of General Surgery Fuzhou General Hospital of Nanjing Military Command were treated with propranolol hydrochloride 3% gel. Changes in hemangioma size, texture, color, tumor blood flow peak were recorded.

[Optimization of processing technology for semen cuscuta by uniform and regression analysis].

Objective: To optimize the best preparation technology for the contains of total flavornoids, polysaccharides, the percentage of water and alcohol-soluble components in Semen Cuscuta herb processing.

Methods: UV-spectrophotometry was applied to determine the contains of total flavornoids and polysaccharides, which were extracted from Semen Cuscuta. And the processing was optimized by the way of uniform design and contour map.

Diagnostic accuracy of first generation dual-source computed tomography in the assessment of coronary artery disease: a meta-analysis from 24 studies.

The objective of this study is to evaluate the diagnostic accuracy of the first generation dual-source computed tomography (DSCT) in the diagnosis of coronary artery disease (CAD). We selected articles from four databases (Pubmed, Embase, the Cochrane central register of controlled trials (CENTRAL) and Chinese biomedical literature database. The strict study selection was made, and two reviewers independently extracted data back-to-back from included studies.