Publications by authors named "Ya-min Pan"
Article Synopsis
- - Colorectal cancer (CRC) is a common cancer, and this study investigates the anti-tumor effects of Celastrol, a compound known for its potential in various cancers, specifically targeting CRC.
- - The research demonstrated that Celastrol inhibits proliferation in CRC cells and significantly reduces tumor growth in mice, identifying 69 candidate proteins linked to its effects, with Shoc2 being the most notable.
- - Celastrol works by inhibiting the ERK1/2 signaling pathway, which is crucial for cancer cell movement and growth, and down-regulation of Shoc2 decreases tumor cell proliferation and migration.
Background: Self-expandable metallic stents (SEMSs) are widely used for palliation of malignant gastric outlet obstruction (GOO). There are two types of SEMS, covered and uncovered, each with its own advantages and disadvantages. We aimed to compare the efficacy and safety between uncovered and covered SEMSs in the palliation of malignant gastric outlet obstruction.
View Article and Find Full Text PDFBackground And Study Aims: There are limited data on the role of antireflux biliary stents. This single-center randomized trial compared the endoscopic use of partly covered antireflux metal stents (pcARMS) with that of standard uncovered self-expandable metal stents (ucSEMS) for the palliation of nonhilar malignant biliary obstruction.
Patients And Methods: Between August 2007 and February 2012, patients with nonhilar malignant biliary obstruction were randomly assigned to treatment with either pcARMS or ucSEMS.
Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis.
Gastrointest Endosc
February 2014
Background: Esophagectomy is the conventional treatment for Barrett's esophagus with high-grade dysplasia and intramucosal cancer. Endotherapy is an alternative treatment.
Objective: To compare the efficacy and safety of these 2 treatments.
Intramural duodenal hematoma (IDH) is a rare complication following endoscopic retrograde cholangiopancreatography (ERCP). Blunt damage caused by the endoscope or an accessory has been suggested as the main reason for IDH. Surgical treatment of isolated duodenal hematoma after blunt trauma is traditionally reserved for rare cases of perforation or persistent symptoms despite conservative management.
View Article and Find Full Text PDFBackground: Endoscopic management of biliary or pancreatic strictures by stent insertion is well established. However, some high-grade strictures are refractory to dilation and stent placement with conventional methods.
Objective: To evaluate the safety and efficacy of the wire-guided electrotomy technique in dilating stiff biliary and/or pancreatic stenoses when ordinary methods failed.
Objective: To evaluate the efficacy and safety of endoscopic papillary large-balloon dilation (EPLBD) combined with limited endoscopic sphincterotomy (EST) for the removal of large biliary duct stones (≥10 mm).
Methods: Data of patients who underwent an attempted removal of large bile duct stones by limited EST followed by EPLBD (≥12 mm in diameter) from April 2006 to October 2011 in our center were reviewed. Clinical characteristics, endoscopic methods and outcomes of the patients were collected and analyzed.
Background & Aims: Limited endoscopic sphincterotomy with large balloon dilation (ESBD) is an alternative to endoscopic sphincterotomy (ES) for removing bile duct stones, but it is not clear which procedure is most effective. We compared the 2 techniques in removal of bile duct stones.
Methods: Between September 2005 and September 2011, 156 consecutive patients with suspected of having, or known to have, common bile duct stones were randomly assigned to groups that underwent ES or ESBD.
Endoscopic stenting for post-transplant biliary stricture: usefulness of a novel removable covered metal stent.
J Hepatobiliary Pancreat Sci
September 2011
Background: Endoscopic management of biliary anastomotic stricture (AS) following liver transplantation (LT) remains challenging. There are no dedicated self-expandable metal stents (SEMS) for this setting.
Methods: A short fully covered SEMS (FCSEMS) with a retrieval suture was designed.
Background: Antireflux stents that prevent duodenal biliary reflux may improve biliary drainage and prolong stent patency. However, the use of antireflux metal stents (ARMSs) in the human biliary system has not been reported.
Objective: To evaluate the safety and efficacy of ARMSs for the palliation of unresectable distal biliary malignancies.