Publications by authors named "Ya-ling Cui"
Article Synopsis
- Liang-Yan-Yi-Zhen-San (LYYZS) is an ancient Chinese herbal formula that promotes the browning of white adipose tissue, which is important for fat metabolism.
- The study identified 52 active ingredients within LYYZS and screened 1,560 ingredient-related targets linked to its effects, while also analyzing gene expression changes in mice.
- The network pharmacology analysis revealed 10 key active ingredients that contribute to browning, demonstrating a comprehensive approach to identifying substances that enhance fat burning.
Background: Hypothermia is a complex pathophysiological response that can be life-threatening in low-temperature environment because of impaired thermoregulation. However, there is currently no clinically effective drugs that can prevent or treat this disease. Brown adipose tissue (BAT) activation or browning of white adipose tissue (WAT) is a promising therapeutic strategy to prevent or treat hypothermia.
View Article and Find Full Text PDFObjective: To establish the spectrum-effect relationship network model of Qizhiweitong granules promoting gastrointestinal motility for providing scientific basis for its quality control and efficacy evaluation.
Methods: The Latin hypercube sampling was used to establish full-time multi-wavelength fusion fingerprints of different compatibility groups of Qizhiweitong granules. At the same time, the appreciation rate, the contents of cGMP and NO in small intestine smooth muscle cells after administrated drugs were determined.
Objective: To investigate the immediately effects of inhaled aerosolized iloprost in adult patients with severe pulmonary arterial hypertension (PAH) secondary to congenital heart diseases (CHD).
Methods: Adult patients with severe PAH secondary to CHD (n = 165) were included in this study. Right heart catheterization was performed, Pulmonary and systemic blood flow, the oxygen consumption VO(2) (ml/min) were calculated using Fick's principle.
[The trend of cancer mortality from 1988 to 2005 in Kaifeng county, China].
Zhonghua Yu Fang Yi Xue Za Zhi
June 2007
Objective: To investigate the time trends of cancer mortality among residents in Kaifeng county, Henan province.
Methods: Data on cancer mortality from the vital registration system in Kaifeng county from 1988 to 2005 was analyzed. A total of 9543 death records (5974 males and 3567 females) due to malignant tumors were studied.