Publications by authors named "Ya-kun Du"

Article Synopsis
  • Leigh syndrome is a mitochondrial disorder caused by mutations in nuclear and mitochondrial genes, with the Ndufa3 gene's role in the disease still not fully understood.
  • Researchers analyzed a family with suspected Leigh syndrome, conducting brain imaging and genetic testing on three affected siblings, who presented early-onset symptoms like abnormal muscle tone and developmental delays.
  • The study identified novel compound heterozygous mutations in the Ndufa3 gene in all affected individuals, marking the first report linking these mutations to Leigh syndrome and enhancing the understanding of the gene's impact on the disease.
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Background: Bivalirudin, a direct thrombin inhibitor, is used in anticoagulation therapies as a substitute for heparin, especially during cardiovascular procedures such as percutaneous coronary intervention.

Aim: To explore the effect of bivalirudin on myocardial microcirculation following an intervention and its influence on adverse cardiac events in elderly patients with acute coronary syndrome (ACS).

Methods: In total, 165 patients diagnosed with acute myocardial at our hospital between June 2020 and June 2022 were enrolled in this study.

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Objective: To evaluate the feasibility and the clinical practicality of the design about the hollowed titanium stick supporting the femoral head and preventing it from collapsing.

Methods: From Jan.2003 to Jun.

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