Publications by authors named "Ya-hong Yang"
The rostral ventrolateral medulla (RVLM) is a pivotal region in the central regulation of blood pressure (BP). It has been documented that silent information regulator 2 homolog 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD)-dependent multifunctional transcription regulatory factor, has many cardiovascular protective effects. However, the role and significance of SIRT1 in the central regulation of cardiovascular activity, especially in RVLM, remains unknown.
View Article and Find Full Text PDFIn this study, we investigated the effectiveness and microbial mechanism of biofertilizer on reducing ammonia volatilization in farmland soil. Pot experiments were carried out to explore the effects of biofertilizer (BB) and chemical fertilizer on soil ammonia volatilization, crop yield and quality, and soil microbial community. Four fertilization strategies were tested, namely no fertilizer (CK), 100% chemical fertilizer (C), 50% BB and 50% chemical fertilizer (B1), and 100% BB (B2).
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- Monoclonal gammopathy of renal significance (MGRS) can cause kidney issues and lead to conditions like Henoch-Schönlein purpura nephritis (HSPN), particularly in adults who don't respond to traditional treatments.
- A case study details a patient with HSPN related to IgA-κMGRS, who faced challenges like skin purpura and nephrotic syndrome but ultimately improved after a specific treatment regimen.
- The study emphasizes the importance of recognizing MGRS in adult patients with HSPN, as proper diagnosis and tailored treatments can significantly enhance patient outcomes.
Objective: Centrally acting antihypertensive action of moxonidine is a result of activation of Imidazoline-1 receptor (I1R) in the rostral ventrolateral medulla (RVLM). Hypertension shows an increase in reactive oxygen species (ROS) in the RVLM. The present objective was to determine the phosphoinositide-3 kinase (PI3K) signaling pathway involved in the effect of moxonidine on ROS generation in the RVLM of spontaneously hypertensive rat (SHR).
View Article and Find Full Text PDFThe imbalance between angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) in the brain has been reported to contribute to cardiovascular dysfunction in hypertension. Exercise training (ExT) is beneficial to hypertension and the mechanism is unclear. This study was aimed to determine if ExT improves hypertension via adjusting renin angiotensin system in cardiovascular centers including the rostral ventrolateral medulla (RVLM).
View Article and Find Full Text PDFAngiotensin-1-7 [Ang-(1-7)], acting via the Mas receptor in the central nervous system, is involved in the regulation of cardiovascular activity. Nitric oxide (NO) is implicated as an important modulator in the nucleus tractus solitarii (NTS), a key region involved in control of cardiovascular activity. The aim of the present study was to determine the role of phosphatidylinositol 3-kinase (PI3K) signaling in mediating the effect of Ang-(1-7) on NO generation in the NTS.
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- The study examined medical waste management practices in western China across 74 healthcare facilities, revealing potential health and environmental risks associated with improper waste handling.
- Results indicated that primary hospitals produced more medical waste (0.61 kg per bed per day) than secondary hospitals, primarily due to poor separation of domestic and medical waste.
- To improve management, the study emphasized the need for national regulations, qualified personnel, and comprehensive training programs, alongside adequate financial support and monitoring from local authorities.