Publications by authors named "Ya-chen An"
This study aims to investigate the predictive values of the Chinese Stroke Scale (CSS) and National Institutes of Health Stroke Scale (NIHSS) in the prognosis of patients with acute cerebral infarction.A total of 399 patients with acute cerebral infarction were assessed using CSS and NIHSS within 1 day after admission. Then, the receiver operating characteristic (ROC) curves were established, and the area under the curves of these 2 scoring systems was compared.
View Article and Find Full Text PDF[Risk factors on the recurrence of ischemic stroke and the establishment of a Cox's regression model].
Zhonghua Liu Xing Bing Xue Za Zhi
August 2011
Objective: To investigate the risk factors and establish the Cox's regression model on the recurrence of ischemic stroke.
Methods: We retrospectively reviewed consecutive patients with ischemic stroke admitted to the Neurology Department of the Hebei United University Affiliated Hospital between January 1, 2008 and December 31, 2009. Cases had been followed since the onset of ischemic stroke.
[Study on mannose-binding protein gene polymorphisms and susceptibility to pulmonary tuberculosis].
Zhonghua Liu Xing Bing Xue Za Zhi
December 2006
Article Synopsis
- The study investigates the link between specific genetic variations of the mannose-binding protein (MBP) and the risk of developing pulmonary tuberculosis (TB) among patients and healthy individuals.
- Researchers analyzed genetic mutations in the MBP gene from 125 TB cases and 198 controls, using a case-control design and advanced statistical techniques to assess risk factors.
- Results indicated that certain MBP mutations (especially MBP-52) were more common in TB patients, suggesting a potential genetic susceptibility to the disease.
[Study on the association of INT4 and 3'UTR polymorphism of natural-resistance-associated macrophage protein 1 gene with susceptibility to pulmonary tuberculosis].
Zhonghua Liu Xing Bing Xue Za Zhi
January 2006
Article Synopsis
- The study examined how variations in the NRAMP1 gene are linked to the risk of pulmonary tuberculosis (TB) among Han individuals in Northern China.
- Researchers used a case-control method with 124 pairs of TB patients and healthy controls, employing genetic testing techniques to analyze specific NRAMP1 polymorphisms (3'UTR and INT4).
- The results indicated that the 3'UTR TGTG+/del genotype increased TB susceptibility, while no significant link was found with the INT4 polymorphism, although it did affect the disease's characteristics.