Upregulation of microRNA-191 can serve as an independent prognostic marker for poor survival in prostate cancer.

MicroRNA-191 (miR-191) has been identified as being upregulated in several types of cancers, and plays the role of oncogene. The expression of miR-191 has been found to be upregulated in prostate cancer tissues as well as cell lines. In this study, we analyzed the correlation of miR-191 expression with clinicopathologic factors and prognosis in prostate cancer.

The role of circulating miR-146a in patients with rheumatoid arthritis treated by Tripterygium wilfordii Hook F.

Rheumatoid arthritis (RA) is polygenic autoimmune disease with unclear etiology. MicroRNAs (miRNAs) play a critical role in the pathogenesis of RA. The objective of this study was to evaluate the role of miR-146a in patients with RA receiving Tripterygium wilfordii Hook F (TwHF) treatment.

[Protective effect of haliotidis on the oxidative damage in the human lens epithelial cells].

Objective: To study the influence of haliotidis extractive on the oxidative damage in the human lens epithelial cells cultured in vitro.

Methods: Experimental study. Cultured human lens epithelial cells in vitro were intervened with hydrogen peroxide caused oxidative damage model, at the same time added different concentrations of concha haliotidis extractive.