Geographical classification of population: Analysis of amino acid in fingermark residues using UHPLC-QQQ-MS/MS combined with machine learning.

Objective: To determine the living regions of individuals based on amino acids in fingermark residues and to establish a rapid and accurate regional classification method using machine learning.

Methods: A total of 71 fingermark donors from six different provinces in various regions of China were selected. The content of 18 amino acids in their fingermarks was detected using UHPLC-QQQ-MS/MS.

Toward multidimensional information: A derivatization-free UHPLC-QqQ MS/MS method for amino acid components of fingerprint.

The analysis of fingerprint chemical composition is a meaningful way to excavate the multidimensional information of fingerprint, including the donor profiling information and the age of a fingerprint, which broadens the evidential values of fingerprint, especially for the partial and distorted fingerprint. But the research remains still in the pilot phases or is ongoing. Amino acids are the dominant organic substances in latent sweat fingerprint and influenced by many donor factors.

TOF-SIMS study of latent fingerprints on challenging substrates with the aid of transfer films.

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has been applied in forensic science for fingerprint detection. However, due to limitations of the instrument, it is not always possible to directly sample fingerprints on certain substrates. In this report, we indirectly sampled fingerprints using transfer films.

Visualization of latent fingermarks on fabric using multi-metal deposition (MMD)-A preliminary study.

Multi-metal deposition (MMD) is a versatile fingermarks detection technique adapted from the colloidal gold biolabeling. However, the tedious procedures of MMD makes it receive little attention compared with other methods. The aim of this study is to evaluate the efficacy of MMD technique on several common fabrics, which is considered notoriously challenging for latent fingermark detection.

Expression and Significance of HPV16 E6/E7 mRNAs in the Bronchial Brush and TBNA Cells of Patients With Small Cell Lung Cancer.

Background And Objective: Small cell lung cancer (SCLC) is characterized by rapid growth, strong invasion, and early metastasis. However, the cause of its occurrence remains unclear. High-risk HPV infection is closely related to the occurrence of non-small cell lung cancer and cervical small cell neuroendocrine carcinoma.

Effect of carrier solvent in 1,2-indanedione formulation on the development of fingermarks on porous substrates.

As an important technique for the detection of fingermarks on porous surfaces, 1,2-indanedione is widely used due to its excellent detection performance. In order to optimize the effectiveness of 1,2-indanedione, several institutions have modified the original formulation. In this study, four different 1,2-indanedione formulations were used to treat fingermarks deposited on different porous substrates to determine the most suitable formulation and whether Solstice-PF can be an alternative carrier solvent for the currently used HFE7100.

Distinct miRNA Gene Expression Profiles Among the Nodule Tissues of Lung Sarcoidosis, Tuberculous Lymphadenitis and Normal Healthy Control Individuals.

Sarcoidosis and tuberculosis share similarities in clinical manifestations and histopathological features. We aimed to identify the microRNA (miRNA) profiles of the lymph nodes of individuals with sarcoidosis and of those with tuberculous lymphadenitis to investigate the value of miRNAs in the differential diagnosis of sarcoidosis and tuberculous lymphadenitis. The miRNA profiles of the lymph nodes of individuals with sarcoidosis, those with tuberculous lymphadenitis (TBLN) and controls were detected by miRNA microarray analysis in the age- and sex-matched development group of the controls ( = 3), patients with TBLN ( = 3) and patients with sarcoidosis ( = 3), and the results were validated by quantitative real-time polymerase chain reaction in the validation group of the controls ( = 30), TBLN ( = 30) and patients with sarcoidosis ( = 31).

The Morphological Analysis of Cells in the Bronchoscopic Brushing and TBNA of Patients with Lung Adenocarcinoma.

Biopsy, brushing, and transbronchial needle aspiration (TBNA) are the most common methods for diagnosis of lung adenocarcinoma and are taken during the same diagnostic bronchoscopic procedure. However, it is not clear what the morphological diagnostic criteria of cytology by brushing or TBNA are. A retrospective analysis was performed on 136 patients who underwent video bronchoscopy examination for diagnostic purposes.

Comparative Analysis for Diagnostic Yield of Small Cell Lung Cancer by Cytology and Histology During the Same Bronchoscopic Procedure.

Background: Biopsy, brushing, and transbronchial needle aspiration (TBNA) are the most common methods used for the diagnosis of small cell lung cancer during the same diagnostic bronchoscopic procedure. However, it is not clear which method provides better results.

Patients And Methods: A retrospective analysis was performed of 140 patients who had undergone video bronchoscopy for diagnostic purposes.

Bloody pleural effusion--a rare manifestation of sarcoidosis.

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. Pleural effusion is rare in patients with sarcoidosis, occurring in 0.7% to 20% of cumulative series.

Evaluation of DFO/PVP and its application to latent fingermarks development on thermal paper.

A new method for improved development of latent fingermarks on thermal paper by 1,8-diazafluoren-9-one (DFO) treatment is described. Compared with conventional DFO solution, the mixed solution of DFO/PVP (polyvinylpyrrolidone) described here reduces black background staining without removing the thermosensitive layer and develops fingermarks by the reaction of DFO with amino acid deposited on the thermal paper's surface. An advantage of this approach is that the developed fluorescent fingermarks have high contrast and can be observed and photographed when excited in the 515 nm region and observed through an orange-red barrier long-pass filter with no background coloration.

Exploiting the divergent reactivity of aryl-palladium intermediates for the rapid assembly of fluorene and phenanthrene derivatives.

They all fall down: The value of domino processes can be greatly enhanced when the possibility exists for one to selectively diverge from a common intermediate. In preliminary studies the dual reactivity of aryl-palladium intermediates is exploited. A diverse array of fluorene and phenanthrene derivatives were synthesized in a rapid and efficient manner (see scheme).

[Avian influenza (H5N1) cured successfully in human: a case report].

Objective: To improve understanding of avian influenza in humans by presenting a case of avian influenza (H(5)N(1)).

Methods: Clinical and laboratory data of this case of avian influenza (H(5)N(1)) in humans were described, and related literature was reviewed.

Results: The female patient was 31 years old.