Evaluation of risk factors for impulse control disorder in Parkinson's disease in northern China.

Introduction: Impulse control disorder (ICD) is a common non-motor symptom of Parkinson's disease (PD), but its risk factors are still controversial. This study aimed to determine the prevalence of ICD in northern China and analyze the risk factors associated with ICD, multiple ICDs, and four subtypes.

Methods: A total of 285 PD patients were enrolled in this study.

The correlation between possible RBD and cognitive function in Parkinson's disease patients in China.

Objective: Cognitive impairment is an important symptom of Parkinson's disease (PD) and seriously affects patients' quality of life and prognosis. However, its cause is still uncertain. In about one-third of patients, PD is associated with rapid eye movement sleep behavior disorder (RBD), which is an independent risk factor for PD-associated dementia; but whether or not it relates to the cognitive function of patients with nondemented PD is still controversial.

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia.

The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia. In this study, rat models of chronic cerebral ischemia were established by permanent bilateral common carotid artery occlusion and intragastrically administered 9 mg/kg fasudil, a powerful ROCK inhibitor, for 9 weeks.

Hemichorea associated with non-ketotic hyperglycaemia: a case report.

Hemichorea is a rare complication of non-ketotic hyperglycaemia. Patients with this syndrome have classically longstanding, poorly controlled diabetes. Here, we report a patient presenting hemichorea without diabetic history.

Quality of life and its influencing factors in patients with post-traumatic epilepsy.

Objective: To observe the quality of life in patients with post-traumatic epilepsy and discuss the influencing factors.

Methods: We assessed 105 patients with post-traumatic epilepsy and 100 healthy people as control using Quality of Life Scale-31 (QOL-31), Self-rating Depressing Scale (SDS) and Self-rating Anxiety Scale (SAS), and conducted retrospective analysis on the depression, anxiety, site of trauma, control of seizure, EEG and therapeutic compliance.

Results: Patients with post-traumatic epilepsy scored much lower than the control group on QOL-31 (P less than 0.