Publications by authors named "Ya-Yuan Cheng"
Article Synopsis
- Rotor syndrome is a rare and benign genetic disorder linked to mild hyperbilirubinemia caused by mutations in SLCO1B1 and SLCO1B3 genes, leading to impaired bilirubin uptake in the liver.
- A study reported five cases from Taiwan, ranging from 5 to 32 years old, who exhibited conjugated hyperbilirubinemia and genetic variants in the relevant genes, two of whom also had a history of prolonged neonatal jaundice.
- This research marks the first genetic diagnosis of Rotor syndrome in Taiwan, showcasing how advanced genetic testing can improve the diagnosis of rare diseases that may present with mild symptoms.
Objective: To determine the integrity of the sperm plasma membrane, mitochondria, and DNA, which are essential for accurate transmission of genetic material to offspring, and to quantify possible apoptosis and investigate any relationship between these parameters in ejaculated sperm from men with or without varicoceles.
Design: Retrospective study.
Setting: University teaching hospital.
Tumor cells with different origins have different threshold to apoptosis. Hematopoietic (Jurkat, NCI-H929) cells and non-hematopoietic (A549, MCF-7) cells were received hyperbaric oxygen (HBO(2)) treatment from 2.5 to 3.
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