Publications by authors named "Ya-Ya Bai"
Article Synopsis
- Coptis deltoidea (CD) is traditionally used to treat heat-toxin-related conditions but requires processing with wine (PCD) to reduce its bitterness and gastrointestinal side effects.
- The study compared the impacts of CD and PCD on the gastrointestinal system through various tests on mice, including ingredient analysis, inflammation markers, and gut microbiota changes.
- Findings indicated that while CD caused significant gastrointestinal damage and inflammation, PCD showed milder effects and a different impact on gut microbiota composition, suggesting processing with wine improves CD's safety profile.
Background: Long-term use of rhubarb (RH) commonly leads to diarrhea, which can be alleviated by steaming with wine. However, the specific mechanism by which wine steaming alleviates RH-induced diarrhea remains unknown.
Objective: This study aims to reveal the underlying mechanisms of wine steaming in alleviating RH-induced diarrhea by examining small intestinal flora and serum metabolomics.
Article Synopsis
- Long-term use of rhubarb (RH) can lead to gastrointestinal issues like diarrhea, but steaming it with wine (PRH) may help reduce these side effects, though the mechanisms are not fully understood.
- The study aimed to investigate how PRH alleviates diarrhea caused by RH by examining small intestinal flora and immune function.
- Results showed that PRH reduced harmful components, improved fecal characteristics, and mitigated small intestine injuries, indicating a potential beneficial effect of steaming RH with wine.