Publications by authors named "Ya-Xin DU"
Background: The hand, foot and mouth disease (HFMD) was caused by species of Enterovirus A and Enterovirus B in the Asian-Pacific region. Broad-spectrum monoclonal antibodies (mAb) that can bind multiple serotypes of enteroviruses have gradually become a research hotspot in the diagnosis, prevention and treatment of HFMD.
Methods: In this study, a mAb 1H4 was obtained using monoclonal antibody technology by immunizing purified virus particles of Coxsackievirus A5 (CV-A5).
Article Synopsis
- A study was conducted to investigate the ecological effects of different concentrations of traditional microplastics (polystyrene) and biodegradable microplastics (polylactic acid) in soil over 60 days, focusing on microbial activity and carbon metabolism.
- Results showed that microplastics decreased soil pH and increased dissolved organic carbon, with polylactic acid significantly enhancing urease activity while polystyrene did not.
- Higher concentrations of both types of microplastics inhibited microbial carbon metabolism, with polylactic acid having a more significant negative impact than polystyrene due to its tendency to degrade into harmful substances.
Coxsackievirus A10 (CV-A10) is a prevailing causative agent of hand-foot-mouth disease, necessitating the isolation and adaptation of appropriate strains in cells allowed for human vaccine development. In this study, amino acid sequences of CV-A10 strains with different cell tropism on RD and Vero cells were compared. Various amino acids on the structural and non-structural proteins related to cell tropism were identified.
View Article and Find Full Text PDF[Comparison of mechanical properties of three machinable resin ceramic composite materials].
Shanghai Kou Qiang Yi Xue
February 2019
Purpose: This in vitro study was to compare the flexural properties, fracture toughness and hardness of three machinable composite materials.
Methods: Three kinds of resin composite ceramic Upcera Hyramic, 3M Lava Ultimate, Vita Enamic and a glass ceramic Vitablocs Mark II were chosen for the study. Bar-shaped specimens (16 mm×4 mm×1 mm, 2 mm) were prepared for flexural strength experiment; specimens (17 mm×4 mm×3 mm) were prepared for fracture toughness experiment and specimens of 4 mm thickness were prepared for hardness test.