Publications by authors named "Ya-Wen Ao"
For millennia, humans have harnessed thermal energy to treat cancer. However, delivering energy to tumor tissues in traditional hyperthermia remains a significant challenge. Nanotechnology has revolutionized this approach, enabling nanomaterials to target tumors precisely and act as internal heat sources.
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- The study aimed to assess how running multiple marathons impacts heart structure and function in amateur male runners compared to healthy controls.
- Results indicated that amateur marathon runners had larger heart sizes and thicker heart walls, but exhibited lower regional heart muscle strain in certain areas compared to the control group.
- The findings suggest that long-term intense exercise might lead to changes in heart structure, prompting further research to determine if these changes are beneficial or harmful.
Purpose: Numerous studies have implicated the involvement of structure and function of the hippocampus in physical exercise, and the larger hippocampal volume is one of the relevant benefits reported in exercise. It remains to be determined how the different subfields of hippocampus respond to physical exercise.
Methods: A 3D T1-weighted magnetic resonance imaging was acquired in 73 amateur marathon runners (AMR) and 52 healthy controls (HC) matched with age, sex, and education.
Article Synopsis
- * Researchers created redox-sensitive hybrid nanoparticles with varying PEG densities, all maintaining a similar size of approximately 100 nm.
- * Findings reveal that while higher PEG density reduces tumor cell uptake, nanoparticles with controlled PEG stripping enhance accumulation in tumors and improve antitumor activity.
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- This study focuses on developing a non-invasive imaging technique to distinguish between inflammatory masses and malignant gliomas, which is essential for personalized treatment plans for patients.* -
- Current glioma diagnosis relies heavily on risky and complicated pathological biopsies due to a lack of effective non-invasive imaging methods.* -
- The research demonstrates that superparamagnetic iron oxide nanoparticles (SIONPs) can enhance MRI imaging to help differentiate between these conditions, suggesting a new approach for “smart” imaging probes.*