Publications by authors named "Ya-Wei Tang"
Article Synopsis
- - The study investigates the genetic basis of the six-rowed spike phenotype in barley, focusing on the vrs1.a4 allele, which has the same coding sequence as the Vrs1.b4 allele found in two-rowed barley.
- - Genetic analyses demonstrate that a single nuclear gene governs the change in row type between two-rowed and six-rowed barley, with Vrs1 identified as the likely candidate gene located on chromosome 2H.
- - Further investigation shows that reduced expression of vrs1.a4 leads to the six-rowed spike, attributed to a 'TA' dinucleotide deletion in the regulatory region, although more research is needed to confirm the connection between this deletion and decreased Vrs1 expression.
Article Synopsis
- Hulless barley is a vital food source for Tibetans and serves as important livestock feed on the Tibetan Plateau, with its complete mitochondrial genome reported to be 416,675 base pairs.
- The mitochondrial genome contains 34 protein-coding genes, 19 tRNA genes, and 3 rRNA genes, along with various repeats in its structure.
- Phylogenetic analysis suggests that hulless barley is closely related to another plant species based on the comparison of 11 common protein-coding genes across different plant mitochondrial genomes.
Background And Aim: Primary biliary cirrhosis (PBC) is a chronic and progressive cholestatic autoimmune liver disease. Although many studies have evaluated the association between many functional polymorphisms in the vitamin D receptor (VDR) gene and PBC risk, debates still exist. Our aim is to evaluate the association between VDR gene polymorphisms, including TaqI (rs731236), BsmI (rs1544410), and ApaI (rs7975232), and the risk of PBC by a systematic review.
View Article and Find Full Text PDFBackground: The starch granule-associated proteins (SGAPs) are the minor components of the starch granules and a majority of them are believed to be starch biosynthetic enzymes. The Qinghai-Tibet Plateau in China, one of the centres of origin of cultivated barley, is abundant in hull-less barley resources which exhibit high polymorphism in SGAPs.
Results: The SGAPs of hull-less barley from Qinghai-Tibet Plateau were analysed by one-dimensional (1-D) SDS-PAGE, 2-D PAGE and ESI-Q-TOF MS/MS.
Four B-hordein genes, designated BH1-BH4, were cloned using PCR amplification from two hull-less barley cultivars, ZQ7239 and ZQ148, collected from Tibet. The results of sequencing indicated that BH1-BH4 contained complete open reading frames (ORFs). Comparison of their predicted polypeptide sequences with the published sequences suggested that they all share the same basic protein structure.
View Article and Find Full Text PDFThe neuronal glutamate transporter, excitatory amino-acid carrier 1 (EAAC1), plays an important role in the modulation of neurotransmission and contributes to synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and to epileptogenesis. However, the mechanisms that regulate EAAC1 endocytic sorting and function remain largely unknown. Here, we first demonstrate that EAAC1 undergoes internalization through the clathrin-mediated pathway and further show that syntaxin 1A, a key molecule in synaptic exocytosis, potentiates EAAC1 internalization, thus leading to the functional inhibition of EAAC1.
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