Publications by authors named "Ya-Wei Ding"
Ethnopharmacological Relevance: Tongguanteng injection (TGT), the water extract from the stem of the Traditional Chinese hebal medicine of Marsdenia tenacissima (Roxb.) Wight et Arn. has been used as anticancer remedy for decades.
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- Xiaoaiping injection, derived from the root of Marsdenia tenacissima, is a traditional Chinese medicine widely used in China for treating malignant tumors and enhancing the effects of chemotherapeutics like paclitaxel.
- The study aimed to examine how Xiaoaiping injection works together with paclitaxel to inhibit ovarian cancer, focusing on the role of the pregnane X receptor (PXR) in regulating various molecules involved in this process.
- Results indicated that Xiaoaiping injection improved the anti-cancer effects of paclitaxel by reducing the expression of PXR and its associated proteins, leading to increased cell death and decreased tumor growth in an animal model.