Publications by authors named "Ya-Ting Chiu"
Introduction: Although antifungal supplementation reduces the fungal load in the corneal storage medium, consensus is lacking on the influence of dosing and temperature. The study aims to evaluate the impact of eye bank warming protocol and timing of antifungal supplements on efficacy in Optisol-GS and tissue.
Methods: Corneoscleral rims contaminated with Candida albicans (C.
Article Synopsis
- Imatinib is a key drug for treating chronic myeloid leukemia (CML), but some patients develop resistance due to mutations in the BCR-ABL domain, while others may not.
- Research found that higher levels of protective autophagy in IM-resistant K562 (K562R) cells contribute to this resistance, and inhibiting autophagy increased the effectiveness of Imatinib.
- MicroRNA (miR)-199a/b-5p was identified as a potential therapeutic target, as it reduces autophagy and increases cell death in K562R cells by inhibiting WNT2, a gene that regulates autophagy and influences drug sensitivity.
Background: Saussurea involucrata (Kar. et Kir.) commonly known as 'snow lotus' or 'Xue Lian' is an important plant in the traditional Chinese system of medicine.
View Article and Find Full Text PDFSystemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophils.
J Appl Physiol (1985)
October 2009
Phagocytosis and oxidative burst are critical host defense mechanisms in which neutrophils clear invading pathogens. Clearing phagocytic neutrophils by triggering apoptosis is an essential process for controlling inflammation. This study elucidates how various exercise bouts with/without hypoxia affected neutrophil bactericidal activity and subsequent apoptosis in humans.
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