Publications by authors named "Ya-Si Jiang"
Article Synopsis
- Multiple single nucleotide polymorphisms (SNPs) may influence cognitive decline in Parkinson's disease, with unclear mechanisms affecting brain imaging phenotypes.
- A study involving 48 Parkinson's patients and 39 healthy controls used genotyping and advanced MRI techniques to investigate these SNPs' effects on brain structure and function.
- Results showed significant correlations between polygenic risk scores and neural activity/connectivity in specific brain regions, highlighting potential genetic pathways involved in the pathophysiology of Parkinson's disease.
Background: We aimed to evaluate the diagnostic yield of seven-tesla (7T) magnetic resonance imaging (MRI) with post-processing of three-dimensional (3D) T1-weighted (T1W) images by the morphometric analysis program (MAP) in epilepsy surgical candidates whose 3T MRI results were inconclusive or negative.
Methods: We recruited 35 patients with pharmacoresistant focal epilepsy. A multidisciplinary team including an experienced neuroradiologist evaluated their seizure semiology, video-electroencephalography data, 3T MRI and post-processing results, and co-registered FDG-PET.