Publications by authors named "Ya-Qun Li"
Article Synopsis
- The study investigates the effectiveness of an inactivated vaccine in people with prior SARS-CoV-2 infection, measuring their antibody responses over time.
- Individuals previously infected showed strong neutralizing antibody (NAb) levels against both wild-type and Omicron strains post-vaccination, significantly higher than healthy donors.
- NAb levels peaked at 3 months post-vaccination but plateaued by 6 months, indicating long-lasting immunity in those with previous infection compared to a decline in healthy individuals.
Ge Gen Decoction (GGD), a Traditional Chinese Medicine prescription, is mainly used to treat infectious respiratory diseases and can relieve the symptoms of influenza A virus (IAV) infection. However, the underlying mechanism of GGD against IAV infection remains unclear. In this study, we found that GGD had moderate anti-IAV activity in vitro.
View Article and Find Full Text PDFTo study the inhibitory effect of Glehniae Radix petroleum ether part on TGF-β1-induced epithelial mesenchymal transition in non-small cell lung cancer A549 and its possible mechanism. With type Ⅱ epithelial cells of lung cancer A549 as the research object, the experiment was performed in 5 μg•L⁻¹ TGF-β1-induced epithelial mesenchymal transition model,and blank control group, model group and Glehniae Radix petroleum ether group were set up. MTT assay was carried out to detect the effect of petroleum ether extract of Glehniae Radix on the survival of A549 cells.
View Article and Find Full Text PDFOne new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the genus of Lonicera for the first time.
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