Publications by authors named "Ya-Qi Han"

The porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious pathogen in pigs. This study aimed to investigate the impact of PRRSV infection on cellular metabolism, particularly focusing on lipid metabolism to understand its role in promoting viral replication. We conducted a metabolic analysis on MARC-145 cells before and after PRRSV infection.

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Article Synopsis
  • Pseudorabies virus (PRV) causes Aujeszky's disease in pigs, and its relationship with the low-density lipoprotein receptor (LDLR) has not been thoroughly studied.
  • Researchers found that PRV infection increases LDLR levels in various cell types, suggesting that PRV activates sterol-regulatory element-binding proteins (SREBPs) to enhance LDLR expression.
  • Manipulating LDLR levels affected PRV infection rates, indicating its crucial role in the virus's entry and proliferation, which could have implications for controlling outbreaks in the pig industry.
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  • Azo dye wastewater poses significant environmental and health risks, necessitating effective treatment technologies.
  • Photocatalytic methods, particularly using layered black phosphorus nanosheets (LBP), demonstrate effective removal of azo dyes like methyl orange (MO) through degradation processes.
  • The study found that the degradation of MO is most efficient at acidic (pH=3) and alkaline (pH=11) conditions, and involves the attack on the azo bond by hydroxyl radicals, leading to various oxidized degradation products.
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