Publications by authors named "Ya-Ping Yao"

Article Synopsis
  • The study investigates the effectiveness of an inactivated vaccine in people with prior SARS-CoV-2 infection, measuring their antibody responses over time.
  • Individuals previously infected showed strong neutralizing antibody (NAb) levels against both wild-type and Omicron strains post-vaccination, significantly higher than healthy donors.
  • NAb levels peaked at 3 months post-vaccination but plateaued by 6 months, indicating long-lasting immunity in those with previous infection compared to a decline in healthy individuals.
View Article and Find Full Text PDF

Objective: To analyse the subtype and transmission of HIV strain in both HIV infected spouses.

Methods: Reported both HIV infected spouses were selected as objects. Analysis on genetic sequence and high risk behaviors was carried out.

View Article and Find Full Text PDF

Objective: To study the genotypic drug-resistant mutation among treat-naïve or treated patients infected with HIV-1 CRF01_AE in Zhejiang province during 2004-2007.

Methods: HIV-1 pol amplicons (PR + RT) from 13 treated and 43 treat-naïve patients were obtained by reverse transcription-polymerase chain reaction (RT-PCR). The sequences were analyzed for genotypic antiretroviral resistance through online tools (http://hivdb.

View Article and Find Full Text PDF

Objective: Using molecular epidemiology method to characterize human immunodeficiency virus type 1 (HIV-1) subtype CRF01 _ AE strains being prevailed in Zhejiang province.

Methods: Gag fragments of the HIV-1 strains were amplified by nested-polymerase chain reaction (nPCR) from the DNA extracted from whole blood of HIV-1 infected individuals in Zhejiang province. PCR products were sequenced and analyzed by phylogenetic method.

View Article and Find Full Text PDF