Zhonghua Liu Xing Bing Xue Za Zhi
June 2010
Objective: To analyse the subtype and transmission of HIV strain in both HIV infected spouses.
Methods: Reported both HIV infected spouses were selected as objects. Analysis on genetic sequence and high risk behaviors was carried out.
Zhonghua Liu Xing Bing Xue Za Zhi
April 2009
Objective: To study the genotypic drug-resistant mutation among treat-naïve or treated patients infected with HIV-1 CRF01_AE in Zhejiang province during 2004-2007.
Methods: HIV-1 pol amplicons (PR + RT) from 13 treated and 43 treat-naïve patients were obtained by reverse transcription-polymerase chain reaction (RT-PCR). The sequences were analyzed for genotypic antiretroviral resistance through online tools (http://hivdb.
Zhonghua Liu Xing Bing Xue Za Zhi
February 2008
Objective: Using molecular epidemiology method to characterize human immunodeficiency virus type 1 (HIV-1) subtype CRF01 _ AE strains being prevailed in Zhejiang province.
Methods: Gag fragments of the HIV-1 strains were amplified by nested-polymerase chain reaction (nPCR) from the DNA extracted from whole blood of HIV-1 infected individuals in Zhejiang province. PCR products were sequenced and analyzed by phylogenetic method.