Publications by authors named "Ya-Ping Chan"
Article Synopsis
- Cancer metastasis is a major cause of death in cancer patients, and the study investigates whether lycopene can boost the effectiveness of the anticancer drug sorafenib.
- In experiments with mice bearing Lewis lung carcinoma, results showed that lycopene reduced lung metastasis, and its anti-metastatic effects were enhanced when used alongside sorafenib.
- The study revealed that this combination treatment inhibited certain proteins involved in tumor spread (MMP-2 and MMP-9) and reduced the activation of MAPK pathways, suggesting that lycopene may serve as a beneficial addition to sorafenib in treating cancer.
