Publications by authors named "Ya-Peng Yang"
Aims: This study aimed to re-evaluate whether the scoring systems, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were effective in predicting prognosis and severity of COVID-19 patients in the emergency department (ED).
Methods: COVID-19 patients enrolled in this retrospective study divided into the death (DEA) and survival (SUR) groups, the severe/critical (SC) and non-severe/critical (non-SC) groups. The Acute Physiology and Chronic Health Evaluation (APACHE) II, Sequential Organ Failure Assessment (SOFA), National Early Warning Score (NEWS) and CCEDRRN COVID-19 Mortality Score were calculated.
Rhodiola L. is a genus that has undergone rapid radiation in the mid-Miocene and may represent a typic case of adaptive radiation. Many species of Rhodiola have also been widely used as an important adaptogen in traditional medicines for centuries.
View Article and Find Full Text PDFBackground: This study investigated the effects of duodenal-jejunal bypass (DJB) and new biliopancreatic diversion (NBPD) on blood glucose and lipid levels in type 2 diabetes mellitus (T2DM). An additional goal was to explore the potential mechanism or mechanisms underlying the therapeutic effects of surgery on T2DM.
Methods: Rats were fed a high-fat, high-glucose diet and then were intraperitoneally injected with streptozotocin, 35 mg/kg, to induce T2DM.
[Effect of release of hydroxypropylmethyl cellulose on single and bilayer sustained-release matrix tablets].
Beijing Da Xue Xue Bao Yi Xue Ban
April 2013
Objective: To study the influence of HPMC as hydrophilic matrix materials and controlled-layer components on the drug release of sustained-release matrix tablets and bilayer tablets.
Methods: Diltiazem hydrochloride was chosen as the water-soluble model drug to prepare different kinds of matrix tablets and double layer tablets with different formulations, and evaluate how the levels and grades of HPMC affect the drug release in sustained-release tablets and bilayer tablets.
Results: HPMC with high viscosity and the amount of 20%-40% could delay the drug release to certain degree, but it was difficult to further slow down the drug release up to 24 h, especially for a water soluble drug.
[Study of sustained-matrix tablets Ambroxol hydrochloride and potential impact of different fillers on the matrix tablet's scale-up].
Beijing Da Xue Xue Bao Yi Xue Ban
October 2012
Article Synopsis
- The study investigates how different fillers and controlled release materials impact the release profiles of Ambroxol hydrochloride in matrix tablets.
- Single-layer and double-layer matrix tablets were created using various forms of hydroxypropyl methylcellulose and fillers like lactose and microcrystalline cellulose, with in vitro tests used to measure drug release performance.
- Results showed that while lactose-based tablets had significant variation in release rates with changes in matrix material, MCC-based tablets had more consistent release profiles, suggesting that formulation design needs to consider the type of controlled release polymers used for effective scale-up.