Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats.

Objective: Previous studies have indicated that the plasticizer di (2-ethylhexyl) phthalate (DEHP) affects lipid accumulation; however, its underlying mechanism remains unclear. We aim to clarify the effect of DEHP on lipid metabolism and the role of TYK2/STAT1 and autophagy.

Methods: In total, 160 Wistar rats were exposed to DEHP [0, 5, 50, 500 mg/(kg•d)] for 8 weeks.

Expression of human papillomavirus and prognosis of juvenile laryngeal papilloma.

The aim of this study was to evaluate the correlation between clinical behavior and expression of human papillomavirus (HPV) in patients with juvenile laryngeal papillomatosis, in an attempt to develop an effective molecular biological method to predict prognosis. We included 37 patients with juvenile laryngeal papillomatosis in the study group and 10 cases each of juvenile vocal cord polyps and juvenile normal laryngeal mucosa as the control group. We detected HPV by immunocytochemistry and in situ hybridization, identified the virus type, and measured HPV-DNA content using a computer-assisted, color pathological image-analysis system.

[Effect of comprehensive prevention and control of soil-transmitted nematodiasis in Runzhou District of Zhenjiang City].

Objective: To evaluate the effect of comprehensive prevention and control of soil-transmitted nematodiasis in Runzhou District, Zhenjiang City, Jiangsu Province from 1997 to 2012.

Methods: The comprehensive prevention and control measures included the helminthicide, health education, improvement of water supplier and harmless toilets, and these measures were implemented continuously. At the same time, the infection rates of soil-transmitted nematodes, the local economic indicators, and the coverage rates of tap water and harmless toilets were surveyed.

[Effect and cost-benefit of Oncomelania snail control by plowing and planting in Jiaobei Beach of Zhenjiang City].

Objective: To evaluate the effect and cost-benefit of Oncomelania snail control by plowing and planting in Jiaobei Beach of Zhenjiang City.

Methods: In 2009, the measures of building low dike and plowing and planting were implemented in the experimental area of the east part of Jiaobei Beach, while in the control area of the west part of the beach, the molluscacide (niclosamide) was used to control snails. Then, the snail control effects and the cost-benefits of the two groups were compared.

[Clinical characteristics of patients with chronic fatigue syndrome: analysis of 82 cases].

Objective: To analyze the clinical characteristics of Chinese patients suffering from chronic fatigue syndrome (CFS) and provide clinical and laboratory evidence for the study of its etiology and treatment.

Methods: 82 patients with CFS diagnosed based on the CDC criteria 1994 were recruited. History was collected, and physical examination was made.