Publications by authors named "Ya-Long Dang"
Diabetic retinopathy (DR) is an eye disease that causes blindness and vision loss in diabetic. Risk factors for DR include high blood glucose levels and some environmental factors. The pathogenesis is based on inflammation caused by interferon and other nuclear proteins.
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- Malignant glaucoma is a complex post-surgical complication characterized by high intraocular pressure and a shallow anterior chamber, with an incidence of 0.6%-4.0% and risk factors including short axial length and a history of angle closure glaucoma.
- A case of bilateral malignant glaucoma is presented, with each eye having different causes leading to distinct management strategies, yet both eyes maintained a normal anterior chamber and preserved visual function.
- In the left eye, despite multiple surgeries and corneal endothelial failure, a retroendothelial fibrous membrane formed, providing some functional compensation for the damaged corneal endothelium.
Aim: To evaluate the 2-year efficacy and safety of ab interno trabeculectomy with the Trabectome in Chinese primary open angle glaucoma (POAG) patients.
Methods: This was a multicenter, retrospective, observational study and included POAG patients with or without visually-significant cataracts. The Chinese patients were enrolled from three glaucoma centers and a group of comparable Japanese POAG patients was analyzed from our international Trabectome database.
Background: Trabeculectomy is the most efficient surgical treatment. Prevention failure of bleb cicatrix would lead to unsatisfactory postoperative intraocular pressure (IOP) controlling and unsatisfactory success rate. The aim of this study was to evaluate the 5-year outcomes of trabeculectomy with a cross-linked sodium hyaluronate gel implantation for Chinese glaucoma patients.
View Article and Find Full Text PDFBackground: The aim of the study was to evaluate the long-term safety and efficacy of the Trabectome for Chinese glaucoma patients.
Methods: This was a multicenter, retrospective, observational study. Glaucoma patients, except those with neovascular glaucoma, with/without a visually significant cataract were enrolled.
Aim: To investigate the roles of PKC-α/ezrin signals in phagocytosis crisis of retinal pigment epithelium (RPE) cells in light damage model.
Methods: Light induced mice RPE injury model was established by continuously irradiating cool white light at different exposure time (0, 4, 8h light intensity: 4.18×10 J/cm).
Objective: To investigate the biological effects of different intraocular lens (IOL) materials on the adhesion, migration, morphology, and epithelial-to-mesenchymal transition (EMT) of human lens HLEB3 cells.
Materials And Methods: Human HLEB3 cells were seeded onto IOLs composed of four different materials (polymethyl methacrylate (PMMA), silicone elastomer, hydrophilic acrylic, and hydrophobic acrylic). The levels of cellular adhesion, migration, morphology, and EMT were then quantified using a cell viability assay, scratch test, phase contrast microscopy, and immunofluorescence staining, respectively.