Hsa_circ_0005397 promotes hepatocellular carcinoma progression through EIF4A3.

Purpose: The purpose of this study was to explore the expression and potential mechanism of hsa_circ_0005397 in hepatocellular carcinoma progression.

Methods: Quantitative reverse transcription-polymerase chain reaction(qRT-PCR) was used to measure the expression level of hsa_circ_0005397 and EIF4A3 from paired HCC tissues and cell lines. Western Blot (WB) and immunohistochemistry (IHC) were used to verify the protein level of EIF4A3.

Clinical study of standard residual liver volume and transient elastography in predicting poor prognosis of patients after hemihepatectomy.

Background: Liver cancer resection, especially in patients with hemihepatectomy or extended hemihepatectomy, often leads to poor prognosis, such as liver insufficiency and even liver failure and death, because the standard residual liver volume (SRLV) cannot be fully compensated after surgery.

Aim: To explore the risk factors of poor prognosis after hemihepatectomy for hepatocellular carcinoma and evaluate the application value of related prognostic approaches.

Methods: The clinical data of 35 patients with primary liver cancer in Nantong Third People's Hospital from February 2016 to July 2020 were retrospectively analyzed.

Clinical and pathological characteristics of acute kidney injury caused by diquat poisoning.

: Diquat poisoning leads to kidney injury, hepatotoxicity, rhabdomyolysis, gastrointestinal hemorrhage, and respiratory failure. Diquat has high mortality and no specific antidote. The pathology of acute kidney injury caused by diquat poisoning has been mainly investigated in animal studies and autopsies, and typically shows renal tubular necrosis.

PIWIL1 interacting RNA piR-017724 inhibits proliferation, invasion, and migration, and inhibits the development of HCC by silencing PLIN3.

Background: Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Worldwide, liver cancer is the fourth most common cause of cancer-related death. Recent studies have found that PIWI-interacting RNAs (piRNAs) participate in the occurrence and development of various tumors and are closely related to the growth, invasion, metastasis and prognosis of malignant tumors.

Detection of antibiotic-resistant canine origin and the synergistic effect of magnolol in reducing the resistance of multidrug-resistant .

Background: The development of antimicrobial resistance in the opportunistic pathogen has become a global public health concern. Due to daily close contact, dogs kept as pets share the same with their owners. Therefore, the detection of antimicrobial resistance in canine is important, as the results could provide guidance for the future use of antibiotics.

Plasma circRNAs as Biomarkers in Cancer.

The incidence and mortality of cancer are increasing each year. At present, the sensitivity and specificity of the blood biomarkers that were used in clinical practice are low, which make the detection rate of cancer decrease. With advances in bioinformatics and technology, some non-coding RNA as biomarkers can be easily detected through some traditional and new technologies.

The effect and mechanism of YH0618 granule on chemotherapy- induced hair loss in patients with breast cancer: study protocol for a randomized, double-blind, multi-center clinical trial.

Background: Hair loss is one of the most common side effects of chemotherapy, and can cause persistent negative emotions, further affecting therapeutic effects and reducing the quality of life. However, there are no clinically safe and effective methods to solve the problem at present. Our previous clinical and animal studies showed that a medicinal and edible decoction, YH0618, could significantly promote hair growth in cancer patients after chemotherapy, without interfering with the anti-tumor effects of chemotherapy.

miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.

The study aimed to investigate the regulatory effect of miR-146a in proliferation, invasion and migration of breast cancer and its possible mechanism via NM23-H1. The expression levels of miR-146a in breast cancer with different pathological classification were significantly increased, while the expression levels of NM23-H1 were significantly decreased, which were closely correlated. Double luciferase reporter gene was used to verify the target regulatory relationship between miR-146 and NM23-H1 on a human breast cancer cell line.

Sulfonated graphene oxide as an adsorbent for removal of Pb and methylene blue.

One of the major challenges encountered in some conventional nano-structured adsorbents such as graphene oxide (GO) and graphene is the structural limits including serious aggregation and hydrophilic surface in water. And the sulfanilic acid functionalized graphene oxide (SGO) can powerfully attract positively charged pollutants. Therefore, the SGO served as an adsorbent to remove dyes and toxic metal ions from aqueous solution were intensively investigated.

miR-34a expression in human breast cancer is associated with drug resistance.

miR-34a is significantly down-regulated in breast cancer tissues and cell lines, which may be correlated with breast cancer multi-drug resistance (MDR). Here, we conducted cell-based experiments and clinical studies in a cohort of 113 breast cancer samples to analyze miR-34a expression and breast cancer MDR. Expression of miR-34a is down-regulated in the multi-drug resistant MDR-MCF-7 cells compared with its parental cells.

Selective adsorption activities toward organic dyes and antibacterial performance of silver-based coordination polymers.

Two silver-based coordination polymers, [Ag(bpy)(cbda)] (BUC-51) and [Ag(bpy)(cpda)]·(NO)·9HO (BUC-52), have been successfully prepared by slow evaporation at room temperature. These coordination polymers exhibited good adsorptive performances toward series organic dyes with sulfonic groups, which could be ascribed to the AgcdotsO interaction between the silver(I) atoms in CPs and the oxygen atoms from sulfonic groups attached to organic dyes. Both BUC-51 and BUC-52 favoured slow release of Ag ions resulting into outstanding long-term antibacterial abilities toward Gram-negative bacteria, Escherichia coli (E.

Transitional cell carcinoma associated with aristolochic acid nephropathy: most common cancer in chronic hemodialysis patients in China.

Background: The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients.

Methods: The study subjects were 49 cancer patients (1.

[Enriched experiment and endogenous processes of glycogen-accumulating organisms (GAOs)].

Cell decay is an important part of microbiological endogenous processes, which consists of cell death (reduction in the amount of active bacteria) and activity decay (reduction in the specific activity of active bacteria). By means of measuring maximal anaerobic volatile fatty acid (VFA) uptake rates (VFAUR), analyzing 16S rRNA with fluorescence in-situ hybridization (FISH) and observing membrane integrity by live/dead staining, the aerobic decay characteristics of glycogen-accumulating organisms (GAOs) in an enriched GAOs sequencing batch reactor (SBR) system were investigated. It was experimentally identified that a highly enriched culture of GAOs (94%) was obtained by maintaining the temperature at 30 degrees C in the SBR and a high m (COD): m (P) at 100 in the feed.

[Experimental determination of bacterial decay characteristics in biological wastewater treatment system].

The characteristics of cell decay in biological wastewater treatment systems were investigated under aerobic condition, by measuring the decay rate and by determining the death rate with LIVE/DEAD dyeing experiments. It was found that cell decay in biological wastewater treatment systems can be actually described as two parts: decay caused by cell death and decay derived from activity decrease. The experimental results revealed that 60% of cell decay in a nitrifying system was caused by activity decrease and 40% was caused by cell death.

[Experimental study on the effect of COD/P ratios and phosphate recovery on a BNR system].

Based on a BNR system--BCFS, the effect of COD/P and phosphate recovery on the BCFS process was experimentally investigated. The results indicate that a higher P-removal efficiency (87%) and a good P-effluent quality (< or = 0.8 mg x L(-1)) could be maintained at COD/P ratios higher than 24.

Hepatitis B viral infection in maintenance hemodialysis patients: a three year follow-up.

Aim: To observe the prevalence of hepatitis B virus (HBV) infection in maintenance hemodialysis patients.

Methods: Eighty-eight hemodialysis patients who had been receiving hemodialysis regularly for an average of 39.45 +/- 7.