Synopsis of recent research by authors named "Ya-Juan Hao"
- Ya-Juan Hao's research primarily focuses on the role of microRNAs in gallbladder cancer (GBC), demonstrating that specific microRNAs like miR-30a-5p and miR-143-3p act as tumor suppressors by inhibiting cell proliferation, migration, and angiogenesis through various molecular pathways.
- Additionally, Hao has explored the regulatory mechanisms of N(6)-methyladenosine (m(6)A) methylation and its impact on mRNA metabolism, including splicing and export, highlighting key proteins such as YTHDC1 and FTO in these processes.
- The studies also encompass investigations into RNA modifications and their significance in cellular functions and development, suggesting a broader impact on cancer progression and potential therapeutic targets.
