Publications by authors named "Ya-Jing Zhuang"
Cancer Biol Ther
November 2015
Article Synopsis
- USP22 is linked to poor cancer prognosis, but its specific role in nasopharyngeal carcinoma (NPC) has not been previously studied.
- The study employed various methods, including immunohistochemistry and RT-PCR, to find that USP22 expression is significantly higher in NPC cells compared to non-cancerous cells and tissues.
- Knocking down USP22 in NPC cell lines inhibited their growth and altered the cell cycle, suggesting USP22’s involvement in the AKT/GSK-3/Cyclin signaling pathway and identifying it as a potential target for future cancer treatments.
