Publications by authors named "Ya-Jia Lan"

The relationship between colorectal cancer and asbestos exposure has not been fully clarified. This study aimed to determine the associations between asbestos exposure and colorectal cancer. We performed a meta-analysis to quantitatively evaluate this association.

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Objectives: To investigate the polymorphisms in interleukin 17A and interleukin 17F () and their relationship with pulmonary inflammation risk of dust exposed workers.

Methods: A case-control study among 193 subjects, including 67 subjects in case group and 126 in control group was conducted. PCR-RFLP was applied to genotype (G-197A) and (7488T/C).

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Background: In recent years, outbreaks of hand, foot, and mouth disease (HFMD) have increased throughout East and Southeast Asia, especially in mainland China. The disease now presents as an increasingly serious public health threat in China.

Methods: A case-control study was designed to examine risk factors associated with death from severe HFMD.

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Objective: In determine the effect of heat shock protein 70-hom gene (hsp70-hom) polymorphism on the neurobehavioral function of workers exposed to vanadium.

Methods: Workers from the vanadium products and chemical industry were recruited by cluster sampling. Demographic data and exposure information were collected using a questionnaire.

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Objective: To determine the oxidative stress level in peripheral blood of vanadium-exposed workers, as an indication of population health effect of vanadium on human neurobehavioral system.

Methods: 86 vanadium-exposed workers and 65 non-exposed workers were recruited by cluster sampling. A questionnaire was administered to collect demographic and occupational exposure information.

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Objective: To develop a simple structured scale measuring quality of working life (QWL) from the perspective of occupational health and safety.

Methods: We identified the dimensions and items of QWL through literature review, brainstorming and expert panel discussions, and developed a pre-test questionnaire. The pre-test questionnaire was tested in school teachers and revised accordingly.

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Objective: To clarify the dose-response relationship between asbestos dust exposure and lung cancer incidence in chrysotile asbestos miners by fixed cohort study and to investigate the incidence rates of lung cancer in exposure to different concentrations of asbestos dust.

Methods: A retrospective cohort study was conducted in 1932 asbestos miners who registered from January 1, 1981 to December 31, 1988, had worked for at least 1 year, and had no obvious cardiopulmonary diseases; the cohort study began in July 2009 and covered a time span of 29 years (1981 - 2009). The personal information, occupational history, disease history, and health data of these miners were recorded, and the monitoring data on dust concentrations in the mine over the years were collected.

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To explore the effect of magnitude and duration on the performance of Cumulative Sum (CUSUM), with simulation method used on the subject after the insertion of 11 outbreak events into baseline data with Poisson distribution. Sensitivity fluctuated from 9.1% to 100.

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Objective: To reveal the characteristics and stability of the system through the analyzing the surveillance data of respiratory-feverous syndrome via the syndromic surveillance system which was established during the Shanghai World Expo in Pudong New District and provide references for the development and operation optimization on this Mass Gatherings Surveillance Systems.

Methods: Data used was from the surveillance data of respiratory-feverous syndrome collected from Pudong New District Syndromic Surveillance System, through May 1 to October 31, 2010. On the basis of description of data characteristics, correlation analyses were conducted, when compared to the surveillance data of respiratory-feverous syndrome and Pudong influenza-like illness (ILI) used as reference.

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Background: Outbreak detection algorithms play an important role in effective automated surveillance. Although many algorithms have been designed to improve the performance of outbreak detection, few published studies have examined how epidemic features of infectious disease impact on the detection performance of algorithms. This study compared the performance of three outbreak detection algorithms stratified by epidemic features of infectious disease and examined the relationship between epidemic features and performance of outbreak detection algorithms.

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The aim of this study was to determine the main constituents of the essential oil isolated from Fortunella crassifolia Swingle peel by hydro-distillation, and to test the efficacy of the essential oil on antimicrobial activity. Twenty-five components, representing 92.36% of the total oil, were identified by GC-MS analysis.

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Objective: To investigate the distribution characteristics and influencing factors of mental workload of teachers in primary schools.

Methods: National Aeronautics and Space Administration-Task Load Index (NASA-TLX) was used to assess the mental workload levels for 397 teachers of primary schools in a city.

Results: The mental workload (64.

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Objective: To assess occupational stress and quality of working life (QWL) and their association in workers with different jobs.

Methods: The Occupational Stress Inventory Revised Edition (OSI-R) and Quality of Working Life Scale (QWL7-32) were administered to 194 workers in the Liaohe Oilfield. The association between occupational stress and quality of working life was analysed by controlling job types and other confounding variables.

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Objective: To compare the performance of aberration detection algorithm for infectious disease outbreaks, based on two different types of baseline data.

Methods: Cases and outbreaks of hand-foot-and-mouth disease (HFMD) reported by six provinces of China in 2009 were used as the source of data. Two types of baseline data on algorithms of C1, C2 and C3 were tested, by distinguishing the baseline data of weekdays and weekends.

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Objective: To compare the different thresholds of 'moving percentile method' for outbreak detection in the China Infectious Diseases Automated-alert and Response System (CIDARS).

Methods: The thresholds of P(50), P(60), P(70), P(80) and P(90) were respectively adopted as the candidates of early warning thresholds on the moving percentile method. Aberration was detected through the reported cases of 19 notifiable infectious diseases nationwide from July 1, 2008 to June 30, 2010.

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Objective: To analyze the pilot results of both temporal and temporal-spatial models in outbreaks detection in China Infectious Diseases Automated-alert and Response System (CIDARS) to further improve the system.

Methods: The amount of signal, sensitivity, false alarm rate and time to detection regarding these two models of CIDARS, were analyzed from December 6, 2009 to December 5, 2010 in 221 pilot counties of 20 provinces.

Results: The sensitivity of these two models was equal (both 98.

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Objective: To analyze the results of application on China Infectious Diseases Automated-alert and Response System (CIDARS) and for further improving the system.

Methods: Amount of signal, proportion of signal responded, time to signal response, manner of signal verification and the outcome of each signal in CIDARS were descriptively analyzed from July 1, 2008 to June 30, 2010.

Results: A total of 533 829 signals were generated nationwide on 28 kinds of infectious diseases in the system.

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In recent years, for improving the ability of early detection on infectious disease outbreak, many researchers study the disease outbreak detection algorithms, based on many disease surveillance data, expecting to detect the abnormal increasing and cluster of disease and symptom at an early stage by adopting appropriate algorithm. This paper introduces a cumulative sum control chart method, one of statistical process control algorithms widely used in foreign countries and describes its basic principle and characteristic, key points of design, typical examples in application of disease outbreak detection of cumulative sum method, with expect to provide reference for its application in studies of disease outbreak early warning in China.

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Objective: To investigate whether asbestosis is a risk factor for mortality of lung cancer.

Methods: A fixed cohort study was established in an asbestos plant in Chongqing, China, and followed up for 30 years from the beginning of 1972. Basic personal information on life state, cause of death, and diagnosis of asbestosis was collected.

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Objective: To investigate the relationship between simple exposure to chrysotile and lung cancer.

Methods: The nested case-control study method was used. All of lung cancer cases collected from a male fixed prospective cohort with follow-up of 30 years served as cases and a 1:4 matched proportion was used to select non-cancer case as controls.

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Objective: To develop a measurement of safety climate at workplace and assess its validity and reliability.

Methods: According to the theory of preventive safety culture model, a scale including 7 dimensions of 27 items was developed. 342 workers were selected from among all workers of an artificial board factory and were investigated with the developed scale.

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Objective: To investigate the change of neurobehavioral functions of workers with long term exposure to vanadium.

Methods: A total of 106 workers with exposure to vanadium were paired with workers without exposure to vanadium. The WHO-NCTB was employed to assess the neurobehavioral functions.

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Synopsis of recent research by authors named "Ya-Jia Lan"

  • - Ya-Jia Lan's research primarily focuses on the health impacts of occupational exposures, particularly relating to asbestos and vanadium, examining their associations with cancer, pulmonary inflammation, and oxidative stress among exposed workers.
  • - Notable findings include a meta-analysis that evaluated the association between asbestos exposure and colorectal cancer, revealing significant connections that necessitate further exploration, as well as studies identifying genetic polymorphisms linked to pulmonary inflammation risk in dust-exposed workers.
  • - Lan has also contributed to the advancement of occupational health measures, including the development of a quality of working life scale, aiming to improve worker health and safety through a structured assessment of occupational environments.