Publications by authors named "Ya-Chun Ko"
New psychoactive substances are being launched in the drug market at a rapidly growing pace. More than 950 new psychoactive substances have been reported to the United Nations Office on Drugs and Crime. The development of new psychoactive substance abuse has drawn risks on public health and safety.
View Article and Find Full Text PDFSynthetic cathinones, which are a group of β-keto analogs of phenethylamine, have been reported as the most emerging new psychoactive substances in the past decade. The quantity and variety of synthetic cathinones have continued to increase, which poses considerable risks to public health and social security. In this study, an analytical method based on liquid chromatography-tandem mass spectrometry (LCMS/MS) was established for the simultaneous determination of 73 synthetic cathinones and related metabolites in urine.
View Article and Find Full Text PDFArticle Synopsis
- The study introduces a gas chromatography/mass spectrometry (GC-MS) method to detect and measure six synthetic cathinones in urine samples, including mephedrone and methylone.
- It incorporates solid-phase extraction and derivatization, achieving quick analysis within 18 minutes while maintaining strong linearity in results.
- Testing showed that the method is effective for identifying these substances with high precision and accuracy, successfully detecting synthetic cathinones in real urine samples.