A Novel Device for Vergence Exercises: Testing Automatic Dual Rotational Risley Prisms on Asymptomatic Adults and Patients with Convergence Insufficiency.

Introduction: This study investigated the effects of automatic dual rotational Risley prisms (ADRRPs), a mobile phone application-operated device, on vergence abilities in young adults.

Methods: Fifty-six participants aged 20-24 performed vergence exercises. The test group used prisms with power changes from 30Δ base-out to 10Δ base-in, while the control group used plano lenses for 10 min.

Immediate Effects of Vergence Exercises Using Automatic Dual Rotational Risley Prisms on Accommodative Lag and Facility.

Introduction: This study evaluated novel automatic dual rotational Risley prisms (ADRRPs) as a vergence exercise tool for patients with myopia to improve accommodative lag and accommodative facility.

Methods: Participants with myopia aged 20-24 years were recruited. After vergence exercises with prisms (treatment group) or plano lenses (control group) using ADRRPs for 10 min, measurements were taken using an open-field autorefractor (Grand Seiko WAM-5500) at viewing distances of 0.

Effect of nano zinc oxide on proliferation and toxicity of human gingival cells.

Background: Periodontal dressing is used to cover the gum surface and protect the wound after periodontal surgery. Nanomaterials have been widely applied in dentistry in recent years. Zinc oxide (ZnO) is one of the main components of periodontal dressing.

Design Reliable Bus Structure Distributed Fiber Bragg Grating Sensor Network Using Gated Recurrent Unit Network.

The focus of this paper was designing and demonstrating bus structure FBG sensor networks using intensity wavelength division multiplexing (IWDM) techniques and a gated recurrent unit (GRU) algorithm to increase the capability of multiplexing and the ability to detect Bragg wavelengths with greater accuracy. Several Fiber Bragg grating (FBG) sensors are coupled with power ratios of 90:10 and 80:10, respectively in the suggested experimental setup. We used the latest IWDM multiplexing technique for the proposed scheme, as the IWDM system increases the number of sensors and allows us to alleviate the limited operational region drawback of conventional wavelength division multiplexing (WDM).

Using a Machine Learning Algorithm Integrated with Data De-Noising Techniques to Optimize the Multipoint Sensor Network.

In this paper, for an intensity wavelength division multiplexing (IWDM)-based multipoint fiber Bragg grating (FBG) sensor network, an effective strain sensing signal measurement method, called a long short-term memory (LSTM) machine learning algorithm, integrated with data de-noising techniques is proposed. These are considered extremely accurate for the prediction of very complex problems. Four ports of an optical coupler with distinct output power ratios of 70%, 60%, 40%, and 30% have been used in the proposed distributed IWDM-based FBG sensor network to connect a number of FBG sensors for strain sensing.

[Dose-response Relationship of Dexmedetomidine Combined with Sufentail for Postoperative Intravenous Analgesia in Video-assisted Thoracoscopic Surgery].

Objective To investigate the 50% effective dose(ED)and 95% effective dose(ED)of dexmedetomidine(DEX)combined with 0.032 μg/(kg·h)sufentanil as well as its analgesic effect for patient-controlled intravenous analgesia(PCIA)after video-assisted thoracoscopic surgery(VATS).Methods Totally 25 patients undergoing elective VATS were enrolled.

Associated and predictive factors of quality of life in patients with temporal lobe epilepsy.

Objective: Identifying the factors that are correlated with and predictive of reduced quality of life (QOL) is essential to optimize the treatment of epilepsy and the management of comorbidities.

Methods: We analyzed the independent associations between the Quality of Life in Epilepsy-31 (QOLIE-31) inventory and the demographic, clinical, psychiatric, and cognitive variables of 47 consecutive patients with temporal lobe epilepsy (TLE). Predictors of the correlated variables were analyzed by multiple linear regression analysis.

Anti-fibrotic effect of rosmarinic acid on inhibition of pterygium epithelial cells.

Aim: To investigate the anti-fibrosis effect of rosmarinic acid (RA) in pterygium epithelial cells (PECs) to determine if RA is a potent agent for treating pterygium.

Methods: The PECs (1×10 cells/mL) were treated with 100 µmol/L of RA for 1, 3 and 6h. After RA treatment, the cell viability was determined by staining with acridine orange/DAPI and analysis a NucleoCounter NC-3000.

Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

Background: Cisplatin is a potent chemotherapeutic drug for cancer therapy, but it has serious side effects in clinical treatment, particularly nephrotoxicity. The purpose of this study was to evaluate the protective effect of electrolyzed reduced water (ERW) on renal injury caused by cisplatin.

Methods: Animals were divided into four groups as follows: normal control group, cisplatin control group, ERW control group and ERW + cisplatin group.

Inhibitory effects of rosmarinic acid on pterygium epithelial cells through redox imbalance and induction of extrinsic and intrinsic apoptosis.

Pterygium is a common tumor-like ocular disease, which may be related to exposure to chronic ultraviolet (UV) radiation. Although the standard treatment for pterygium is surgical intervention, the recurrence rate of pterygium is high when no effective inhibitory drug is used after surgery. Rosmarinic acid (RA) is a polyphenol antioxidant with many biological activities, including anti-UV and anti-tumor properties.

Lychee flower extract inhibits proliferation and viral replication of HSV-1-infected corneal epithelial cells.

Purpose: Herpes simplex virus type I (HSV-1) is capable of causing a wide array of human ocular diseases. Herpes simplex virus keratitis (HSK)-induced cytopathogenicity together with the chronic immune-inflammatory reaction can trigger stromal scarring, thinning, and neovascularization which may lead to permanent vision impairment. Lychee flower extract (LFE) is known for its antioxidant and anti-inflammatory effects.

B7-H4 expression in bladder urothelial carcinoma and immune escape mechanisms.

B7-H4 is a recently identified member of the B7 family considered to negatively regulate the immune response, and has been associated with the occurrence and development of certain types of tumor. However, little is known regarding the importance of human B7-H4 expression in bladder urothelial carcinoma. In the present study, B7-H4 expression in the tissues and sera of patients with bladder urothelial carcinoma was investigated, along with the clinical significance.

Protective effects of taurine against alloxan-induced diabetic cataracts and refraction changes in New Zealand White rabbits.

The present study examined the protective effects of taurine on alloxan-induced diabetic cataracts and lens damage in male New Zealand White rabbits. The animals were randomly divided into three treatment groups: (1) normal control (vehicle administration); (2) diabetes (100 mg/kg alloxan administration); and (3) diabetes + taurine (1% [w/v] taurine dissolved in drinking water and alloxan administration). The results showed that alloxan-induced diabetes caused significant (p < 0.