Publications by authors named "Ya Xin Yue"
Halogenated aromatic disinfection by-products (DBPs) are a new type of DBPs that have been detected in various water bodies. Previous studies have shown that most of them can induce in vivo toxicity in aquatic organisms. In this study, in order to further investigate the toxic effects and mechanisms of aromatic DBPs, the toxicity and ecological risks of 10 halogenated aromatic DBPs were assessed using the model organism zebrafish.
View Article and Find Full Text PDFThe fatty acid-binding protein (FABP) gene family, which encodes a group of fatty acid-trafficking molecules that affect cellular functions, has been studied extensively in mammals. However, little is known about the gene structure, expression profile, and regulatory mechanism of the gene family in chickens. In the present study, bioinformatics-based methods were used to identify the family members and investigate their evolutionary history and features of gene structure.
View Article and Find Full Text PDFArticle Synopsis
- miR-34a-5p plays a role in regulating lipid metabolism in chickens, particularly in their liver during the peak-laying phase.
- It was found to increase levels of triglycerides and total cholesterol in hepatocytes by inhibiting its target gene, long-chain acyl-CoA synthetase 1.
- The study utilized techniques like dual-luciferase reporter assay, qPCR, and Western blotting to confirm these findings and illustrate the mechanism behind miR-34a-5p's effects on lipid regulation.