Publications by authors named "Ya Qi Zhai"

Background: Bile duct leaks (BDLs) are serious complications that occurs after hepatobiliary surgery and trauma, leading to rapid clinical deterioration. Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line treatment for BDLs, but it is not clear which patients will respond to this therapy and which patients will require additional surgical intervention. The aim of our study was to explore the predictors of successful ERCP for BDLs.

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Article Synopsis
  • This study investigates the potential of F-FDG PET/CT metabolic parameters to predict relapses in type 1 autoimmune pancreatitis (AIP), focusing on 51 patients who didn't receive maintenance therapy after remission.
  • The analysis involved comparing metabolic parameters like SUV, SUVR, and TLG between relapsed and non-relapsed patient groups, finding significant differences in these measurements.
  • The study concluded that certain parameters such as serum IgG and TLG serve as independent predictors for AIP relapse, indicating a promising predictive model with an area under the curve of 0.806.
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Background And Aim: The number of elderly patients with biliary stones is increasing. Endoscopic retrograde cholangiography (ERCP) is considered to be an effective treatment for biliary stones. Having a sound knowledge of the risk factors can help reduce the incidence and severity of complications for ERCP.

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Background: Conventional endoscopic papillectomy (EP) is safe and effective for the treatment of small papilla adenoma to even large laterally spreading tumors of duodenum lesions. As reported by some existing studies, temporarily placing a prophylactic stent in the pancreatic and bile duct can lower the risk of this perioperative complication.

Aim: To evaluate the usefulness, convenience, safety, and short-term results of a novel autorelease bile duct supporter after EP procedure, especially the effectiveness in preventing EP.

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Background And Aims: Direct endoscopic necrosectomy (DEN) with lumen-apposing metal stents (LAMSs) is increasingly used in the management of pancreatic walled-off necrosis (WON). However, it still remains unknown which patients will fail to respond to DEN with LAMSs and require additional surgical intervention. Therefore, the aim of our study was to explore predictors of successful DEN with LAMSs for pancreatic WON.

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Aims: This study aimed to explore the safety and efficacy of endoscopic retrograde cholangiopancreatography (ERCP) in patients over 90 years of age.

Methods: The study included 176 patients aged over 85 years who received their ERCP from February 2002 to January 2021. In the case group (super-elderly group), 44 patients were 90 years old or above.

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Article Synopsis
  • Walled-off necrosis (WON) is a local complication of acute pancreatitis that can be mistaken for pancreatic pseudocysts (PPC), with endoscopic ultrasound (EUS) providing better diagnostic accuracy than CT scans.
  • Two patients underwent EUS-guided treatment for their pancreatic fluid collections, leading to a change in diagnosis from PPC to WON after identifying solid contents through EUS.
  • The treatment avoided direct necrosectomy to minimize bleeding risks by using irrigation, emphasizing the importance of careful intervention in cases with hidden vascular structures.
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Background: Endoscopic resection for large, laterally spreading tumors (LSTs) in the cecum is challenging. Here we report on the clinical outcomes of hybrid endoscopic submucosal dissection (ESD) in large cecal LSTs.

Methods: We retrospectively reviewed data from patients with cecal LSTs ≥ 2 cm who underwent ESD or hybrid ESD procedures between January of 2008 and June of 2019.

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Background And Aims: Gastric schwannoma (GS) is not well clinically recognized and surgical resection (SR) remains the mainstay of treatment. Recently, endoscopic resection (ER) appears to be a safe and effective alternative. However, its comparative outcomes with SR is lacking.

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Background: Neuroendocrine tumors (NETs) are rising in prevalence, particularly with the rectal area. This study evaluated and compared the safety and effectiveness of hybrid endoscopic submucosal dissection (ESD) with those of ESD for rectal NETs and risk factors associated with incomplete endoscopic resection.

Methods: A total of 272 consecutive patients who underwent ESD or hybrid ESD for rectal NETs at the Chinese PLA General Hospital in the period from February 2011 to September 2018 were involved in this study.

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Background And Aims: Endoscopic resection (ER) is an effective and safe method for gastric submucosal tumors, mostly composed of gastrointestinal stromal tumors and leiomyomas. The role of ER in gastric schwannoma (GS) has rarely been described. Our aim was to evaluate the efficacy and safety of ER for GS.

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With the digestive endoscopic tunnel technique (DETT), many diseases that previously would have been treated by surgery are now endoscopically curable by establishing a submucosal tunnel between the mucosa and muscularis propria (MP). Through the tunnel, endoscopic diagnosis or treatment is performed for lesions in the mucosa, in the MP, and even outside the gastrointestinal (GI) tract. At present, the tunnel technique application range covers the following: (1) Treatment of lesions originating from the mucosal layer, .

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  • The study aimed to assess factors influencing the safety and effectiveness of peroral endoscopic myotomy (POEM) for treating achalasia, analyzing data from 439 patients treated between December 2010 and December 2015.
  • Of the patients, a complication rate of 28.7% was noted, with a high treatment success rate of 94.5%, showing significant improvement in symptoms post-procedure.
  • Key findings include that the timing of the procedure and the type of entry incision significantly impact complication rates, with the inverted T incision being the safest option and full-thickness myotomy showing no recurrence of symptoms.
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Endoscopic submucosal dissection (ESD) is a well-established treatment for superficial esophageal squamous cell neoplasms (SESCNs) with no risk of lymphatic metastasis. However, for large SESCNs, especially when exceeding two-thirds of the esophageal circumference, conventional ESD is time-consuming and has an increased risk of adverse events. Based on the submucosal tunnel conception, endoscopic submucosal tunnel dissection (ESTD) was first introduced by us to remove large SESCNs, with excellent results.

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Background/aims: This animal study was performed to evaluate the feasibility and safety of endoscopic transesophageal biopsy by using submucosal tunneling technology novel homemade instruments in the posterior mediastinum.

Methodology: In six survival pigs, a mid-esophageal mucosal incision and a 10-cm submucosal tunnel was created. The endoscope attached to homemade decompression tube was passed through the muscular layers into the posterior mediastinal space.

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