Publications by authors named "Ya Hong You"
[Comparison of the Biological Functions between Human Bone Marrow Derived CD106 Mesenchymal Stem Cells and CD106 Subgroup].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
August 2019
Article Synopsis
- The study aimed to compare the biological functions of bone marrow-derived CD106 mesenchymal stem cells (MSCs) with those of a CD106 subgroup.
- Results showed that CD106 MSCs exhibited superior cell proliferation, adhesion, and metastatic abilities, along with lower levels of cellular senescence compared to the CD106 subgroup.
- Additionally, CD106 MSCs had a significantly higher capacity for nuclear translocation of NF-κB when stimulated by TNF-α, indicating increased responsiveness to inflammatory signals.
[Effect of CD106 Mesenchymal Stem Cell on Bone Marrow Vascular Failure in Patients with Aplastic Anemia].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2018
Objective To investigate the vascularization ability of mesenchymal stem cells(MSCs)and explore its influencing factors in aplastic anemia(AA) patients. Methods MSCs were isolated from the bone marrow of AA patients(AA MSCs) and normal controls(N MSCs) were cultured and then evaluated by flow cytometry and immunofluorescene staining technique.The expression level of vascular cell adhesion molecule-1(CD106) was detected by gene sequencing,and the content and fluorescene intensity of CD106MSCs was determined by fluorescence-activated cell sorting.
View Article and Find Full Text PDF[Long-term Follow-up of Patients with Hepatitis-Associated Aplastic Anemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2017
Objective: To explore the clinical characteristic, therapeutic efficacy and prognosis of patients with hepatitis-associated aplasitc anemia (HAAA).
Methods: the clinical data and labrotatory examination results of 30 cases of HAAA were analyzed retrospectively, the 6-month response ratio and overall survival (OS) were assessed.
Results: HAAA most commonly occured in males, with the occurence rate of males and females was 4:1, the median onset age was 16 (4-43) years old, HAAA oriented focus on sever aplastic anemia (SAA)(4 cases,13%) and very sever aplastic anemia (VSAA)(22 cases,73%).