Research progress of traditional Chinese medicine monomer in treating diabetic peripheral neuropathy: A review.

Diabetes peripheral neuropathy is one of the most common complications of diabetes. Early symptoms are insidious, while late symptoms mainly include numbness, pain, swelling, and loss of sensation in the limbs, which can lead to disability, foot ulcers, amputation, and so on. At present, the pathogenesis is also complex and diverse, and it is not yet clear.

Exploring the causal factor effects of hypothyroidism on ischemic stroke: a two-sample Mendelian randomization study.

Background: Observational studies have suggested a possible association between hypothyroidism and increased risk of ischemic stroke. However, a causal relationship remains unclear.

Methods: Data on single nucleotide polymorphisms (SNPs) associated with hypothyroidism and ischemic stroke were sourced from the FinnGens database and the UK Biobank of European descent.

Network pharmacology analysis of the renal protective effects of bracken (Pteridium aquilinum) using experimental data obtained in an avian (quail) hyperuricemia model.

Objective: To investigate the nephroprotective potential of orally administered bracken extract against renal damage in quails, induced by a high-purine diet, to form a foundation for subsequent clinical studies and applications.

Materials And Methods: A mass spectrometry analysis was conducted on the pteridophyte subjected to steam explosion. Network pharmacological methods were then utilized to pinpoint shared targets and pathways, which suggested that has a capability to counteract renal injury.

Health Effects of Happiness in China.

The demand for improving health status of Chinese residents is growing with the rapid economic development. Happiness, which could be improved by some brief, self-administered, and cost-effective interventions, is reported to be associated with mortality, longevity, and self-rated health. Therefore, it is essential to assess the effect of happiness on health in China.