Scale-based screening and assessment of age-related frailty.

As the population ages, the prevalence of age-related frailty increases sharply, which increases the risk of poor health status of older adults, such as disability, falls, hospitalization, and death. Across the globe, frailty is moving toward the forefront of health and medical research. Currently, frailty is believed to be preventable and reversible, so the early identification of frailty is critical.

[Annual therapeutic advances in advanced non-small cell lung cancer in 2024].

This paper reviews the clinical progress achieved in 2024 in the field of advanced non-small cell lung cancer (NSCLC), both nationally and internationally. In the area of targeted therapy, particularly for rare mutations, new targets beyond EGFR, ALK, and ROS1 mutations, such as KRAS G12C, HER2, and MET, have gained more clinical validation and approval for targeted drugs in 2024. KRAS G12C inhibitors have also shown significant improvements in disease control rates for patients.

Effects of analgesic delivery on pelvic floor function of primiparous women.

This was an original article, and the objective of this study was to clarify the short-term effects of analgesic delivery on the pelvic floor function of primiparous women. Three hundred primiparas who delivered vaginally in The Affiliated Hospital of Kangda College of Nanjing Medical University from January 2022 to July 2022 were enrolled, and were divided into control and intervention groups. The control accepted traditional delivery without special analgesic intervention, while the intervention group accepted intraspinal block analgesia at the time of delivery.

Unraveling the impact of PFOA toxicity on Zostera marina using a multi-omics approach: Insights from growth, physiological, transcriptomic, and metabolomic signatures.

Perfluorooctanoic acid (PFOA), an anthropogenic organic pollutant known for its persistence, resistance to degradation, and toxicity, has raised significant concerns about its potential ecological impacts. Zostera marina, a common submerged seagrass species in temperate offshore areas, is highly vulnerable to pollutant stressors. However, the impact of PFOA on Z.

R(3780) Resonance Interpreted as the 1^{3}D_{1}-Wave Dominant State of Charmonium from Precise Measurements of the Cross Section of e^{+}e^{-}→Hadrons.

We report the precise measurements of the cross section of e^{+}e^{-}→hadrons at center-of-mass energies from 3.645 to 3.871 GeV.

[Analysis of the prevalence of multimorbidity among adolescents aged 13-18 in Inner Mongolia from 2019 to 2022 and its association with moderate to high-intensity physical activity].

To analyze the changes in the prevalence characteristics of multimorbidity among adolescents aged 13-18 in Inner Mongolia from 2019 to 2022 and to explore the association between multimorbidity and moderate to high-intensity physical activity among them. A stratified random cluster sampling method was used to select students aged 13-18 in Inner Mongolia every September from 2019 to 2022. Physical examinations, demographic characteristics, and depression-related surveys were conducted to analyze the multimorbidity of overweight, obesity, high blood pressure, myopia, spinal curvature abnormality, and depression.

[Comprehensive evaluation of resistance to Cd stress in mycorrhizal seedlings formed by different genotypes of and ].

To select the mycorrhizal seedlings of with excellent Cd-resistance and explore the mechanism of promoting the resistance to Cd stress of , nine species of isolated from different hosts infected to form mycorrhizal seedlings, were cultured in Cd-contaminated soil for three months. We conducted the principal component analysis (PCA) on biomass, root structure, and photosynthesis, and evaluated the Cd tolerance of mycorrhizal seedlings by membership function. The results showed that dry and fresh weight of mycorrhizal seedlings under Cd stress were 1.

Boosting the phosphate adsorption of calcite by low Mg-Doping.

Calcite is a promising material choice for adsorbing phosphates because of its abundance and environmentally benign nature. However, the slow adsorption kinetics and hence low adsorption capacity within a short time frame hinders its practical application. In this work, we solve these problems by presenting a low Mg-doped calcite adsorbent, Mg-10.

Tea Consumption and Long-Term Mortality in Very Elderly Individuals With or Without Cardiovascular and Cerebrovascular Disease: Findings From a Sample of 19664 Chinese.

Background: The association between tea consumption and mortality among very elderly individuals, with or without cardiovascular and cerebrovascular diseases (CCD), including stroke, remains unclear. This study hypothesised that a significant association exists.

Methods: We analysed data from two waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS), spanning 1998/2000 to 2018, with a maximum follow-up of 20 years.

Bound-State Beta Decay of ^{205}Tl^{81+} Ions and the LOREX Project.

Stable ^{205}Tl ions have the lowest known energy threshold for capturing electron neutrinos (ν_{e}) of E_{ν_{e}}≥50.6  keV. The Lorandite Experiment (LOREX), proposed in the 1980s, aims at obtaining the longtime averaged solar neutrino flux by utilizing natural deposits of Tl-bearing lorandite ores.

Potassium escaping balances the degree of graphitization and pore channel structure in hard carbon to boost plateau sodium storage capacity.

Biomass holds significant potential for large-scale synthesis of hard carbon (HC), and HC is seen as the most promising anode material for sodium-ion batteries (SIBs). However, designing a HC anode with a rich pore structure, moderate graphitization and synthesis through a simple process using a cost-effective precursor to advance SIBs has long been a formidable challenge. This is primarily because high temperatures necessary for pore regulation invariably lead to excessive graphitization.

[Comparison of effect of different medial boundaries in laparoscopic right hemicolectomy: a meta-analysis].

To investigate and compare the clinical efficacy and prognosis of D3 lymphadenectomy/complete mesocolic excision in treatment of right colon cancer with different medial boundaries. We searched The Cochrane Library, Pubmed, Embase, CBM, VIP, CNKI, and WanFang data bases for superior mesenteric artery (SMA)-oriented and superior mesenteric vein (SMV)-oriented D3 lymphadenectomy/complete mesocolic excision from inception to December, 2023. The resultant data were submitted to meta-analysis using RevMan 5.

[Salidroside alleviates high glucose and ethanol-induced pyroptosis in insulinoma cells].

This study established a pyroptosis injury model by stimulating insulinoma cells(INS-1) of rats with high glucose(HG) and observed the impact of additional ethanol(ET) exposure on cell pyroptosis, as well as the intervention effect of salidroside(SAL). INS-1 cells were cultured and divided into a normal control group(NG), an HG group, an HG + ET(100 mmol·L~(-1)) group, and an HG + ET + SAL(1-100 μmol·L~(-1)) group. After 72 hours of treatment, cell viability was assessed using the cell counting kit-8(CCK-8) assay.

Characteristics of corneal aberration in patients with bilateral keratoconus and unilateral corneal Vogt's striae.

Aim: To assess the corneal high-order aberration (HOA) and its correlation with corneal morphological parameters in patients with bilateral keratoconus (KCN) and unilateral Vogt's striae.

Methods: A total of 168 eyes of 84 patients with KCN, whose corneas had definite signs of unilateral Vogt's striae, were enrolled. Corneal HOA and morphological parameters were measured using Pentacam HR.

Prediction of Lung Adenocarcinoma Driver Genes Through Protein-Protein Interaction Networks Utilizing GenePlexus.

Lung adenocarcinoma, a subtype of lung cancer, is produced by uncontrolled proliferation of somatic cells affected by some tumorigenic factors. The origin of this disease can be attributed to the concept of "cancer driver," which links the occurrence of tumor with specific changes in some key genes. These key genes can be identified at various molecular levels.

Prevalence and risk factors of headache in Chinese with stroke: a cross-sectional study based on CHARLS.

Background: Stroke ranks as the second leading cause of death worldwide. Meanwhile, headaches are considered the second leading cause of disability, and they often occur as a stroke complication. However, insufficient attention has been given to the treatment and rehabilitation of headaches among stroke patients, and the research on the epidemiology and risk factors of headaches in stroke patients in China is limited.

Cooperative Multiscale-Assembly for Directional and Hierarchical Growth of Highly Oriented Porous Organic Cage Single-Crystal Microtubes and Arrays.

The directional assembly of porous organic molecules into long-range ordered architectures, featuring controlled hierarchical porosity and oriented pore channels with defined spatial arrangements, is a fundamental challenge in chemistry and materials science. Herein, using porous organic cages as starting units, we present a cooperative multiscale-assembly strategy enabling the simultaneous alignment of pore channels and directional hierarchical growth in a single step. At the microscopic level, we employed double solvents to manipulate the intermolecular packing of microporous tetrahedral [4+6] imine cages (CC1 and CC3), resulting in pore channel orientation.

Nuclear Structure of Dripline Nuclei Elucidated through Precision Mass Measurements of ^{23}Si, ^{26}P, ^{27,28}S, and ^{31}Ar.

Using the Bρ-defined isochronous mass spectrometry technique, we report the first determination of the ^{23}Si, ^{26}P, ^{27}S, and ^{31}Ar masses and improve the precision of the ^{28}S mass by a factor of 11. Our measurements confirm that these isotopes are bound and fix the location of the proton dripline in P, S, and Ar. We find that the mirror energy differences of the mirror-nuclei pairs ^{26}P-^{26}Na, ^{27}P-^{27}Mg, ^{27}S-^{27}Na, ^{28}S-^{28}Mg, and ^{31}Ar-^{31}Al deviate significantly from the values predicted assuming mirror symmetry.

Synthesis of in-plane MoC/MoO heterostructures by a novel spatial-confined partial oxidation approach for enhanced TEA sensing.

In-plane heterostructures exhibit extraordinary chemical and electron transfer properties, which have received remarkable research attention. However, the synthesis of an in-plane MoC/MoO heterostructure has been rarely reported, and the deep investigation of the effect of its fine structure on reactivity is of great significance. Notably, the in-plane heterostructures endow the material with abundant grain boundaries, which facilitate the formation of surface acid sites and active oxygen species, thus contributing to the sensing performance.

Topological flat bands in a family of multilayer graphene moiré lattices.

Moiré materials host a wealth of intertwined correlated and topological states of matter, all arising from flat electronic bands with nontrivial quantum geometry. A prominent example is the family of alternating-twist magic-angle graphene stacks, which exhibit symmetry-broken states at rational fillings of the moiré band and superconductivity close to half filling. Here, we introduce a second family of twisted graphene multilayers made up of twisted sheets of M- and N-layer Bernal-stacked graphene flakes.