Publications by authors named "Y-W Jeon"

Article Synopsis
  • A study assessed the 1-year treatment of nilotinib in patients with autosomal dominant spinocerebellar ataxia (ADSCA), focusing on treatment efficacy and safety.
  • Although the average ataxia severity, measured by the SARA score, did not significantly improve for the overall group, 62.5% of participants were considered 'responsive' based on score improvements.
  • Serum proteomic analysis identified specific proteins that may help predict which patients are likely to respond to nilotinib, suggesting potential pathways for improving treatment strategies for ADSCA.
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To identify the vascular alteration by photodynamic therapy (PDT), the utilization of high-resolution, high-speed, and wide-field photoacoustic microscopy (PAM) has gained enormous interest. The rapid changes in vasculature during PDT treatment and monitoring of tumor tissue activation in the orthotopic pancreatic cancer model have received limited attention in previous studies. Here, a fully two-axes waterproof galvanometer scanner-based photoacoustic microscopy (WGS-PAM) system was developed for in vivo monitoring of dynamic variations in micro blood vessels due to PDT in an orthotopic pancreatic cancer mouse model.

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Article Synopsis
  • A global Task Force aimed to standardize COVID-19 treatment recommendations and determine consensus through a voting process where 70% agreement was required.* -
  • They recommended using remdesivir and dexamethasone for acute COVID-19 pneumonia and suggested therapeutic anticoagulant therapy for related complications, while advising against hydroxychloroquine outside clinical trials.* -
  • However, the Task Force couldn't reach a consensus on post-hospital care for survivors, highlighting areas where more research is needed, particularly for mental health screenings.*
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Background and Purpose- Based on its mechanism, the use of balloon guide catheters (BGCs) may be beneficial during endovascular treatment, regardless of the type of mechanical recanalization modality used-stent retriever thrombectomy or thrombaspiration. We evaluated whether the use of BGCs can be beneficial regardless of the first-line mechanical endovascular modality used. Methods- We retrospectively reviewed consecutive acute stroke patients who underwent stent retriever thrombectomy or thrombaspiration from the prospectively maintained registries of 17 stroke centers nationwide.

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In a previous multinational, randomized, double-blind, double-dummy study, levodopa-carbidopa intestinal gel (LCIG) was tolerable and significantly improved 'off' time in advanced Parkinson's disease (PD) patients. However, efficacy and safety in the Asian population has not yet been demonstrated. In this open-label study, efficacy and safety of LCIG were assessed in Japanese, Korean, and Taiwanese advanced PD patients with motor complications not adequately controlled by available PD medication.

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