Liquid crystalline microphases of DNA molecules complexed with compounds of platinum(II).

The formation of liquid crystalline microphases (0.3 M NaClO4, and 120 and 170 mg PEG/ml) from low-Mr DNA (salmon sperm) complexed with cis and trans dichlorodiamine-platinum(II) was investigated. It was shown that the amplitude of the negative band in the CD spectrum, characteristic of a liquid crystalline microphase of DNA, decreased upon complexing with platinum compounds.