Publications by authors named "Y Yoshihara"

Background: Social dysfunctions can affect the quality of life (QOL) of patients with schizophrenia. The autism-spectrum quotient (AQ) is a widely used measure of innate autistic traits. However, in patients with schizophrenia, the score may represent the severity of autism-like social dysfunctions as a consequence of symptoms.

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Electroconvulsive therapy (ECT) is one of the most effective treatments for depression. ECT induces volume changes in the amygdala, a key center of anxiety. However, the clinical relevance of ECT-induced changes in amygdala volume remains uncertain.

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Article Synopsis
  • Autism spectrum disorder (ASD) is a complex lifelong condition, and this study aimed to create a classifier using resting-state fMRI from a large group of 730 Japanese adults to identify its neural and biological features.
  • The developed classifier showed effectiveness in differentiating individuals with ASD from neurotypical controls across various countries, including the US and Belgium, and it also applied to children and adolescents.
  • Importantly, the study found that the classifier identified crucial functional connections related to social interaction difficulties and neurotransmitter activity, and it linked ASD with similar neurobiological factors seen in ADHD and schizophrenia, enhancing understanding of related mental health disorders.
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We conducted a 4-year temperature manipulation experiment in a Mongolian grassland to examine the effect of daytime and nighttime warming on grassland recovery after grazing exclusion. After constructing a livestock exclusion fence in the grassland, we established daytime and daytime-and-nighttime warming treatments within the fenced area by a combination of open-top chambers (OTC) and electric heaters. We measured the numbers of plants and aboveground biomass by species after recording percentage vegetation cover every summer for three warming treatments inside the fence-non-warming, daytime warming, and daytime-and-nighttime warming-and for the grassland outside of the fence.

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