Publications by authors named "Y Yonezawa"
Background: The Tohoku Medical Megabank Project has initiated the Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study) including genomic and omics investigations, and conducted a self-administered food frequency questionnaire with the response option "constitutionally unable to eat or drink it" for individual food items (TMM-FFQ) for pregnant women. This study evaluated the validity of the TMM-FFQ among pregnant women.
Methods: Participants comprised 122 pregnant women aged ≥20 years residing in Miyagi Prefecture who completed weighed food records (WFRs) for 3 days as reference intake and the TMM-FFQ during mid-pregnancy.
Recently, web-based dietary assessment tools for the targeted population have been developed and used to estimate the dietary intake level in several epidemiological studies. This study aimed to examine the validity of estimating energy and nutrient intake by the web-based 24 h dietary recall (Web24HR), which we developed for the Japanese population. Overall, 228 adults aged ≥20 years who agreed to participate were included.
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- PRRSV is a significant virus affecting the swine industry, and this study is the first to report NADC34-like strains found in Japan.
- Serum samples from 18 piglets in Okinawa were analyzed, showing all samples matched a specific sublineage, identified as sublineage 1.5 of Lineage 1.
- Although NADC34-like strains are known to cause severe outbreaks, the farm experienced only a temporary spike in piglet mortality, indicating a need for further research on these strains and the potential for new variants.
Article Synopsis
- The Tohoku Medical Megabank Project (TMM) aims to enhance personalized healthcare using genomic data, focusing on evaluating a self-administered food frequency questionnaire (TMM-FFQ) among Japanese adults.
- Participants (89 men and 124 women) recorded their food intake over 12 days and completed the FFQ in 2019 and 2021 to assess the questionnaire's validity and reproducibility.
- Results showed that the TMM-FFQ demonstrated reasonable validity and reproducibility, with strong correlation coefficients for food group intakes and high percentages of accurate classification across food categories.
Core planar cell polarity genes and in predisposition to congenital vertebral malformations.
Proc Natl Acad Sci U S A
April 2024
Congenital scoliosis (CS), affecting approximately 0.5 to 1 in 1,000 live births, is commonly caused by congenital vertebral malformations (CVMs) arising from aberrant somitogenesis or somite differentiation. While Wnt/ß-catenin signaling has been implicated in somite development, the function of Wnt/planar cell polarity (Wnt/PCP) signaling in this process remains unclear.
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