Publications by authors named "Y Yatomi"
Article Synopsis
- The study focuses on establishing reference values for the tricuspid annulus (TA) geometry in a Japanese population, which is important for tricuspid valve surgery related to tricuspid regurgitation (TR).
- Using 3D echocardiography, researchers analyzed data from 96 healthy Japanese subjects and found that TA area and circumference strongly correlate with body surface area, while age has a weaker correlation.
- Gender differences in TA geometry were significant in younger subjects, with males showing larger TA area and smaller diameters compared to females, but these differences lessened with age.
Dupilumab-induced psoriatic dermatitis and arthritis in a patient with atopic dermatitis were effectively managed with upadacitinib, highlighting the use of Janus kinase inhibitors as a possible treatment for biologic therapy side effects.
View Article and Find Full Text PDFObjective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality, and its incidence is increasing due to endemic obesity. HCC is sexually dimorphic in both humans and rodents with higher incidence in males, although the mechanisms contributing to these correlations remain unclear. Here, we examined the role of sphingosine kinase 2 (SphK2), the enzyme that regulates the balance of bioactive sphingolipid metabolites, sphingosine-1-phosphate (S1P) and ceramide, in gender specific MASH-driven HCC.
View Article and Find Full Text PDFBackground: To avoid an invasive renal biopsy, noninvasive laboratory testing for the differential diagnosis of kidney diseases is a desirable goal. As sphingolipids are demonstrated to be involved in the pathogenesis of various kidney diseases, we investigated the possible usefulness of the simultaneous measurement of urinary sphingolipids for differentiating kidney diseases.
Materials And Methods: Residual urine specimens were collected from patients who had been clinically diagnosed with chronic glomerulonephritis (CGN), diabetic mellitus (DM), systemic lupus erythematosus (SLE), and arterial hypertension (AH).