Publications by authors named "Y Yakushiji"
Article Synopsis
- Cerebral small vessel disease (SVD) can lead to various cerebrovascular issues, but research on sex differences in SVD is limited.
- This study analyzed data from over 20,000 patients with acute ischemic stroke to examine whether the presence and severity of cerebral microbleeds (CMB) and other SVD markers differ between males and females.
- Results showed that males had more frequent CMB while females had fewer lacunes but higher severe white matter hyperintensities, indicating distinct SVD characteristics based on sex.
Article Synopsis
- The study investigates the rs671 genetic variant, linked to "Asian flush," and its influence on mild cognitive impairment (MCI) in a cohort of older adults in Japan.
- It found that the rs671 variant significantly increases the risk of MCI in individuals who do not consume alcohol habitually, indicating a possible independent effect on cognitive health.
- The research emphasizes the importance of considering genetic and lifestyle factors in developing targeted dementia prevention strategies tailored to specific populations.
A 47-year-old man was admitted to our hospital because of sudden-onset motor aphasia and right hemiplegia. His past medical history was notable for left craniotomy and hematoma evacuation following a traumatic brain hemorrhage approximately 40 years earlier, for which dural grafting was performed. He also had a history of three lobar hemorrhages in the left hemisphere since the age of 42 years.
View Article and Find Full Text PDFWe investigated the effects of individual and cumulative cerebral small vessel disease (SVD) markers on long-term clinical outcomes in spontaneous intracerebral hemorrhage (sICH) patients. This prospective, single-center cohort study was conducted from 2012 to 2019. SVD markers, including lacunae, cerebral microbleeds, white matter hyperintensity (WMH), and perivascular spaces in the basal ganglia, were assessed to calculate a summary SVD score.
View Article and Find Full Text PDFArticle Synopsis
- A study investigated the prescription status of antiplatelet therapy (APT) for patients with non-cardioembolic ischemic stroke (NCIS) and ischemic heart disease (IHD) over three phases from 2015 to 2020.
- Findings showed that while the initial dual antiplatelet therapy (DAPT) rate for NCIS increased over time, many patients stopped taking it after three months, with 25% not receiving any APT afterward.
- In contrast, for IHD patients, the duration of DAPT prescriptions decreased, but the use of single agent therapy (mostly aspirin) increased, highlighting a trend toward shorter DAPT durations in medical care.