Publications by authors named "Y Yahyapour"
Introduction: Northern Iran is one of the regions of the country most affected by COVID-19. The aim of the current study was to examine the demographics, clinical characteristics, and outcomes of suspected and laboratory-confirmed patients <18 years of age hospitalized over two years (during six waves of SARS-CoV-2).
Methods: This retrospective cohort study examined hospitalized patients with suspected SARS-CoV-2 infection in Babol, northern Iran.
Objective: This study aimed to explore the potential relationship between viral infections and gastrointestinal (GI) malignancies, focusing on the presence of KRAS G12D mutations. Specifically, we investigated the association of viral agents, including human papillomavirus (HPV) and Epstein-Barr virus (EBV), with KRAS G12D mutations in GI cancers to better understand their combined role in cancer development.
Methods: This cross-sectional study comprised 92 patients diagnosed with GI cancer and 100 healthy individuals in the control group.
Background: Although vaccination is the most effective and specific approach for prevention of infectious diseases, but in a small percentage of vaccinated person's breakthrough infections can occur. This study aimed to determine the effectiveness of different common vaccines in this area.
Methods: 109 COVID-19 vaccinated patients were enrolled, with different types of vaccines (Sinopharm, AstraZeneca, Sputnic, Bharath, CovIran Barkat and Pasto-CoV) and time of administration in 2021 in Babol, Iran.
Article Synopsis
- Plasmid-mediated quinolone resistance (PMQR) in extended-spectrum β-lactamase (ESBL)-producing bacteria is linked to treatment failures and higher mortality, prompting a study in Babol, Iran, to assess the prevalence of PMQR genes.
- From March 2022 to February 2023, 95 clinical isolates were analyzed, revealing that 71.57% were ESBL producers, with high frequencies of specific PMQR genes detected.
- The study found a significant correlation between ESBL and PMQR genes, demonstrating the need for improved antimicrobial stewardship and surveillance to combat the spread of resistant bacteria.
Article Synopsis
- - This study focused on analyzing the presence and condition of the HPV-16 virus in various cervical lesions, including non-cancerous, precancerous, and cancerous tissues.
- - Researchers used quantitative real-time PCR to measure the viral loads of two HPV-16 genes (E2 and E6) in 132 cervical samples, finding significant differences in these loads across the lesion types.
- - The results indicated that the E2 gene viral load is a strong biomarker for differentiating lesion types, with E2 and E6 showing high specificity and sensitivity in identifying cancerous samples.