Publications by authors named "Y Y Yuen"

Dengue fever is a serious health issue, particularly in tropical countries like Singapore. We have previously found that dengue virus (DENV) recruits human plasmin in blood meal to enhance the permeability of the mosquito midgut for infection. Here, using biolayer interferometry, we found that neither kringle-4 nor kringle-5 plasmin domains alone binds well to dengue virus.

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Article Synopsis
  • Poor sleep quality is linked to cerebrovascular diseases, which can lead to cognitive decline and strokes as people age, but research on non-drug treatments is limited.
  • A study will involve Chinese participants aged 60-90 with mild vascular cognitive impairment and sleep issues, who will be assigned to different stimulation groups (hf-tRNS, tACS, or sham) over two weeks while their brain activity is monitored.
  • The study aims to evaluate the safety, feasibility, and effectiveness of high-frequency transcranial random noise stimulation (hf-tRNS) to improve cognitive function and sleep quality in these patients.
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Purpose: To report continuing diffuse retinal dysfunction following resolution of immune reconstitution uveitis (IRU) in patients with cytomegalovirus retinitis (CMVR).

Methods: Retrospective case series describing two patients with IRU following CMVR who underwent serial fundus photography and macular optical coherence tomography. One patient had serial electrophysiology.

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Background: Diabetic retinopathy (DR) screening using colour retinal photographs is cost-effective and time-efficient. In real-world clinical settings, DR severity is frequently graded by individuals of different expertise levels. We aim to determine the agreement in DR severity grading between human graders of varying expertise and an automated deep learning DR screening software (ADLS).

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